CAS 5465-65-6

1-(4-Chloro-3-nitrophenyl)ethanone

Description:

1-(4-Chloro-3-nitrophenyl)ethanone, with the CAS number 5465-65-6, is an organic compound characterized by its functional groups and aromatic structure. It features a phenyl ring substituted with both a chloro group and a nitro group, which contribute to its reactivity and physical properties. The presence of the ethanone moiety indicates that it is a ketone, which typically exhibits a carbonyl group (C=O) that is polar and can participate in various chemical reactions, such as nucleophilic additions. This compound is likely to be a solid at room temperature, with moderate solubility in organic solvents due to its aromatic nature. Its chlorinated and nitro-substituted phenyl ring may impart unique electronic properties, making it of interest in various chemical syntheses and applications, including pharmaceuticals and agrochemicals. Safety data should be consulted, as compounds with halogen and nitro groups can exhibit toxicity and environmental hazards.

Formula: C₈H₆ClNO₃

InChI: InChI=1S/C8H6ClNO3/c1-5(11)6-2-3-7(9)8(4-6)10(12)13/h2-4H,1H3

InChI key: InChIKey=YEVPHFIFGUWSMG-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=CC(C(C)=O)=CC=C1Cl

Synonyms:

• 1-(4-Chloro-2-Nitro-Phenyl)Ethanone
• 1-(4-Chloro-3-Nitrophenyl)Ethanone
• 1-Acetyl-4-chloro-3-nitrobenzene
• 2-Chloro-5-acetylnitrobenzene
• 3'-Nitro-4'-Chlorocetophenone
• 3′-Nitro-4′-chloroacetophenone
• 4-Acetyl-1-chloro-2-nitrobenzene
• Acetophenone, 4′-chloro-3′-nitro-
• Ethanone, 1-(4-chloro-3-nitrophenyl)-
• NSC 25820
• 4′-Chloro-3′-nitroacetophenone

1-(4-Chloro-3-nitrophenyl)ethanone

CAS: 5465-65-6

Formula: C₈H₆ClNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 199.5911

Ref: IN-DA0033VT

4''-Chloro-3''-nitroacetophenone

CAS: 5465-65-6

Formula: C₈H₆ClNO₃

Molecular weight: 199.60

Ref: 7W-GK9214

4'-Chloro-3'-nitroacetophenone

CAS: 5465-65-6

4'-Chloro-3'-nitroacetophenone

Formula: C₈H₆ClNO₃

Purity: ≥95%

Color and Shape: colourless to pale cream crystals

Molecular weight: 199.59g/mol

Ref: 54-OR0027

4'-Chloro-3'-nitroacetophenone

CAS: 5465-65-6

Formula: C₈H₆ClNO₃

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Green powder to crystal

Molecular weight: 199.59

Ref: 3B-C2321

4-Chloro-3-nitroacetophenone

CAS: 5465-65-6

4-Chloro-3-nitroacetophenone is a phenothiazine drug that is used in the treatment of lung conditions. It binds to the active site of human cytochrome P450, which is an enzyme that metabolizes many drugs and other foreign substances. 4-Chloro-3-nitroacetophenone inhibits the reaction by binding to the chloride ion and preventing it from leaving the enzyme's active site, which is necessary for its function. The drug has been shown to have a high affinity for protozoan tetrahymena, an organism that has been widely used as a model system in biochemistry research. 4-Chloro-3-nitroacetophenone also inhibits biochemical reactions involving nucleophilic substrates such as quinoline derivatives. The reaction rate of these substrates is decreased by this drug due to its ability to compete with water molecules for the nucleophilic reaction intermediate.

Formula: C₈H₆ClNO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 199.59 g/mol

Ref: 3D-FC54339

4-Chloro-3-nitroacetophenone

CAS: 5465-65-6

Formula: C₈H₆ClNO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 199.59

Ref: 10-F045204