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CAS 5466-11-5

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2-chloro-9-pentofuranosyl-9H-purine

Description:
2-Chloro-9-pentofuranosyl-9H-purine, with the CAS number 5466-11-5, is a purine nucleoside analog characterized by the presence of a chlorine atom at the 2-position of the purine ring and a pentofuranosyl sugar moiety. This compound exhibits properties typical of nucleosides, including the ability to participate in biochemical processes such as nucleic acid synthesis. Its structural features contribute to its potential biological activity, particularly in antiviral and anticancer research, as it may interfere with nucleic acid metabolism. The chlorine substitution can enhance its stability and alter its interaction with enzymes and receptors compared to its non-chlorinated counterparts. Additionally, the compound's solubility, reactivity, and pharmacokinetic properties are influenced by its specific molecular structure, making it a subject of interest in medicinal chemistry. Overall, 2-chloro-9-pentofuranosyl-9H-purine represents a significant compound for further exploration in therapeutic applications.
Formula:C10H11ClN4O4
InChI:InChI=1/C10H11ClN4O4/c11-10-12-1-4-8(14-10)15(3-13-4)9-7(18)6(17)5(2-16)19-9/h1,3,5-7,9,16-18H,2H2
SMILES:c1c2c(nc(Cl)n1)n(cn2)C1C(C(C(CO)O1)O)O
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100
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50
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90
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95
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100
Found 2 products.
  • 2-Chloro-9-(β-D-ribofuranosyl)purine

    CAS:
    <p>2-Chloro-9-(beta-D-ribofuranosyl)purine is a Nucleoside Derivative - Halo-nucleoside, 6-Deaminopurine nucleoside.</p>
    Formula:C10H11ClN4O4
    Color and Shape:Solid
    Molecular weight:286.67
  • 2-Chloro-9-(b-D-ribofuranosyl)purine

    CAS:
    <p>2-Chloro-9-(b-D-ribofuranosyl)purine is a monophosphate nucleoside that has been shown to have antiviral and anticancer activity. It is synthesized through the chemical conversion of 2,4-dichloropyrimidine with b-D-ribofuranose. This product is a novel nucleoside analogue that has been shown to be an activator of DNA synthesis. In addition, 2-chloro-9-(b-D ribofuranosyl) purine may be used as a phosphoramidite for oligonucleotide synthesis.</p>
    Purity:Min. 95%

    Ref: 3D-NC163103

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