CAS 5466-77-3

octyl P-methoxycinnamate

Description:

Octyl P-methoxycinnamate, also known as octinoxate, is an organic compound commonly used as a UV filter in sunscreens and cosmetic products. It is characterized by its ability to absorb UVB radiation, thereby protecting the skin from sunburn and potential skin damage. The substance has a relatively low molecular weight and is lipophilic, which allows it to be easily incorporated into various formulations. Octyl P-methoxycinnamate is typically colorless to pale yellow and has a mild, pleasant odor. It is stable under normal conditions but can degrade when exposed to prolonged sunlight, which may reduce its effectiveness as a UV filter. The compound is generally considered safe for use in cosmetics, although some studies have raised concerns about its potential for skin irritation and endocrine disruption. Regulatory agencies have established guidelines for its concentration in cosmetic products to ensure consumer safety. Overall, octyl P-methoxycinnamate plays a significant role in photoprotection, making it a popular ingredient in sun care formulations.

Formula: C₁₈H₂₆O₃

InChI: InChI=1/C18H26O3/c1-4-6-7-8-16(5-2)21-18(19)14-11-15-9-12-17(20-3)13-10-15/h9-14,16H,4-8H2,1-3H3/b14-11+

InChI key: InChIKey=YBGZDTIWKVFICR-UHFFFAOYSA-N

SMILES: C(=CC(OCC(CCCC)CC)=O)C1=CC=C(OC)C=C1

Synonyms:

• (2R)-2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
• (5-Methylheptyl) 3-(4-methoxyphenyl)-2-propenoate
• 1-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
• 2-Ethylhexyl 3-(4-Methoxyphenyl)Prop-2-Enoate
• 2-Ethylhexyl 3-(4-methoxyphenyl)-2-propenoate
• 2-Ethylhexyl methoxycinnamate
• 2-Ethylhexyl-4-Methoxycinnamate
• 2-Ethylhexyl-4-methoxycinnamat
• 2-Ethylhexyl-p-methoxycinnamate
• 2-Ethylhexyl3-(4-methoxyphenyl)acrylate
• 2-Propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester
• 2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
• 3-(4-Methoxyphenyl)-2-propenoic acid 2-ethylhexyl ester
• 4-Methoxycinnamate de 2-ethylhexyle
• 4-Methoxycinnamic Acid 2-Ethylhexyl Ester
• 4-Metoxicinamato De 2-Etilhexilo
• Escalol 557
• Escalol 557NB
• Escalol 557T
• Ethylhexyl Methoxycinnamate
• Ethylhexyl p-methoxycinnamate
• Eusolex 2292
• Eusolex UV-Pearls OMC
• Jeescreen OMC
• Neo Heliopan AV
• Nomcort TAB
• Nomcort TAB-R
• Nsc 26466
• OMC
• Octinoxate
• Octyl 4-methoxycinnamate
• Octyl methoxycinnamate
• Parsol MCX
• Parsol MCX-SA
• Parsol MOX
• Propen-2-Enoate, 3-(4-Methoxyphenyl)-, 2-Ethylhexyl
• Solarom OMC
• Sun Caps 664
• Sunscreen AV
• Tinosorb OMC
• Uvinal MC 80
• Uvinul 3088
• Uvinul MC 80
• Uvinul MC 80N
• Uvinul MC 90
• p-Methoxycinnamic acid 2-ethylhexyl ester
• 3-(4-Methoxy-phenyl)-acrylicacid2-ethyl-hexylester
• PARSOL MCX-XR
• 2-Propenoicacid,3-(4-methoxyphenyl)-,2-ethylhexylester
• TIMTEC-BB SBB008472
• 2-ethvlhexvlmethoxvcinnamate
• 4-METHOXYCINNAMIC ACID OCTYL ESTER
• 3-(4-methoxyphenyl)-2-propenoicaci2-ethylhexylester
• OCTYL P-METHOXYCINNAMATE
• 2-ETHYLHEXYL TRANS-4-METHOXYCINNAMATE
• Isooctyl-4-methoxycinnamate

2-Ethylhexyl 4-Methoxycinnamate

CAS: 5466-77-3

Formula: C₁₈H₂₆O₃

Purity: >97.0%(GC)

Color and Shape: Colorless to Yellow to Green clear liquid

Molecular weight: 290.40

Ref: 3B-M1082

Octinoxate

CAS: 5466-77-3

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc not elsewhere specified or included

Formula: C₁₈H₂₆O₃

Color and Shape: Pale Yellow Liquid

Molecular weight: 290.18819

Ref: 45-1477900

Octinoxate

CAS: 5466-77-3

Octinoxate (Octyl 4-methoxycinnamate) is an organic compound that is used is in sunscreens and other cosmetics to absorb UV-B rays from the sun.

Formula: C₁₈H₂₆O₃

Purity: 99.93%

Color and Shape: Less To Pale Yellow Viscous Liquid (Ntp 1992) Physical Description Colorless To Pale Yellow Viscous Liquid (Ntp 1992)

Molecular weight: 290.40

Ref: TM-T0073

Octinoxate

CAS: 5466-77-3

Formula: C₁₈H₂₆O₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 290.3972

Ref: IN-DA003H7Y

Octinoxate

CAS: 5466-77-3

Octinoxate

Purity: ≥98%

Molecular weight: 290.4g/mol

Ref: 54-BUP18876

2-Ethylhex-1-yl 4-methoxycinnamate

CAS: 5466-77-3

2-Ethylhex-1-yl 4-methoxycinnamate

Formula: C₁₈H₂₆O₃

Purity: 97% （trans）

Color and Shape: colourless liquid

Molecular weight: 290.40g/mol

Ref: 54-OR5266

Octinoxate-13C-d3 (Octyl 4-Methoxycinnamate-13C-d3)

CAS: 5466-77-3, 83834-59-7

Formula: C₁₇₁₃CH₂₃D₃O₃

Color and Shape: Pale Yellow Liquid

Molecular weight: 294.41

Ref: 4Z-O-072002

2-Ethylhexyl Trans-4-Methoxycinnamate

CAS: 5466-77-3

2-Ethylhexyl Trans-4-Methoxycinnamate

Purity: 99%

Molecular weight: 290.4g/mol

Ref: 54-OR1030708

2-Ethylhexyl 4-methoxycinnamate

CAS: 5466-77-3

Formula: C₁₈H₂₆O₃

Color and Shape: Neat

Molecular weight: 290.40

Ref: 04-C13342000

Octinoxate

CAS: 5466-77-3

Formula: C₁₈H₂₆O₃

Color and Shape: Neat

Molecular weight: 290.40

Ref: 86-MM0729.00

Octinoxate

CAS: 5466-77-3

Applications Octinoxate is used in the preparation of polymer particles for the preparation of UV protective materials.
References Steeley, K. et al.: Dyes. Pigments. 105, 12 (2014); Couteau, C. et al.: Pharm. Dev. Tech., 19, 315 (2014); Chem. and Eng. News page 22, Aug. 6 (2018)

Formula: C₁₈H₂₆O₃

Color and Shape: Neat

Molecular weight: 290.40

Ref: TR-O257500

Octinoxate-d3

Controlled Product

CAS: 5466-77-3

Formula: C₁₃D₃H₂₃O₃

Color and Shape: Colourless

Molecular weight: 293.42

Ref: TR-O257503

2-Ethylhexyl 3-(4-methoxyphenyl)acrylate

CAS: 5466-77-3

Formula: C₁₈H₂₆O₃

Purity: 95.0%

Color and Shape: Clear

Molecular weight: 290.403

Ref: 10-F237840

OCTYL METHOXYCINNAMATE

CAS: 5466-77-3

Purity: 95%

Molecular weight: 290.4030151

Ref: 10-F844632

Octinoxate-13C3

Controlled Product

CAS: 5466-77-3

Formula: C₃C₁₅H₂₆O₃

Color and Shape: Neat

Molecular weight: 293.38

Ref: TR-O257502

Octyl 4-methoxycinnamate

CAS: 5466-77-3

Octyl 4-methoxycinnamate (OMC) is an organic compound that is used in wastewater treatment. It is also a potent skin sensitizer and can cause allergic contact dermatitis. The genotoxic effects of OMC have been studied in vitro, where it showed the ability to induce DNA mutations and chromosomal aberrations. OMC also has synergistic effects with UV radiation, which increases the risk of skin cancer. OMC can cause immunological sensitization, autoimmune diseases, and genotoxicity in humans when it is absorbed through the skin or inhaled into the lungs. This chemical has been shown to cause genetic damage in human serum at concentrations as low as 0.1 ppm, with a no observed adverse effect level of 1 ppm.

Formula: C₁₈H₂₆O₃

Purity: Min. 96%

Color and Shape: Clear Liquid

Molecular weight: 290.4 g/mol

Ref: 3D-FO29526