CAS 5466-84-2

4-Nitrophthalic anhydride

Description:

4-Nitrophthalic anhydride is an organic compound characterized by its anhydride functional group and a nitro substituent on the phthalic structure. It appears as a pale yellow to light brown solid and is known for its high reactivity, particularly in electrophilic aromatic substitution reactions due to the electron-withdrawing nature of the nitro group. This compound is primarily used in the synthesis of various dyes, pharmaceuticals, and agrochemicals. It is also utilized as a chemical intermediate in the production of polyesters and other polymers. 4-Nitrophthalic anhydride is soluble in organic solvents such as acetone and chloroform but has limited solubility in water. Safety precautions are necessary when handling this compound, as it can be harmful if inhaled or ingested, and may cause skin and eye irritation. Proper storage in a cool, dry place away from incompatible materials is essential to maintain its stability and prevent degradation.

Formula: C₈H₃NO₅

InChI: InChI=1S/C8H3NO5/c10-7-5-2-1-4(9(12)13)3-6(5)8(11)14-7/h1-3H

InChI key: InChIKey=MMVIDXVHQANYAE-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)O1)=CC=C(N(=O)=O)C2

Synonyms:

• 1,3-Isobenzofurandione, 5-nitro-
• 4-Nitro Phthalic Anhydride
• 4-Nitro-1,2-Benzenedicarboxylic Acid Anhydride
• 4-Nitro-2-Benzofuran-1,3-Dione
• 4-Nitrophthalic acid anhydride
• 5-Nitro-1,3-isobenzofurandione
• 5-Nitro-2-Benzofuran-1,3-Dione
• 5-Nitroisobenzofuran-1,3-dione
• 5-Nitrophthalic anhydride
• Ethyl {[(3,4-Dichlorophenyl)Carbamoyl]Oxy}Methylcarbamate
• NSC 26424
• Phthalic anhydride, 4-nitro-

4-Nitrophthalic anhydride, tech. 90%

CAS: 5466-84-2

4-Nitrophthalic anhydride is used an an intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the leg

Formula: C₈H₃NO₅

Purity: 90%

Color and Shape: Pale yellow to cream, Crystals or powder or crystalline powder

Molecular weight: 193.11

Ref: 02-L08020

5-Nitroisobenzofuran-1,3-dione

CAS: 5466-84-2

Formula: C₈H₃NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 193.1131

Ref: IN-DA003LWH

4-Nitrophthalic anhydride

CAS: 5466-84-2

4-Nitrophthalic anhydride

Purity: 98%

Molecular weight: 193.11312g/mol

Ref: 54-OR60036

4-Nitrophthalic Anhydride

CAS: 5466-84-2

Formula: C₈H₃NO₅

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 193.11

Ref: 3B-N0246

4-Nitrophthalic anhydride

CAS: 5466-84-2

Formula: C₈H₃NO₅

Molecular weight: 193.11

Ref: 7W-GK7452

3-Nitrophthalic Anhydride

Controlled Product

CAS: 5466-84-2

Applications An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472).
References Denny, W., et al.: J. Med. Chem., 33, 814 (1990), Anon., et al.: Curr. Med. Chem., 10, 321 (2003),

Formula: C₈H₃NO₅

Color and Shape: Light Yellow

Molecular weight: 193.113

Ref: TR-N515320

4-Nitrophthalic anhydride

CAS: 5466-84-2

Formula: C₈H₃NO₅

Purity: 97%

Color and Shape: Power or Crystalline Powder or Solid or Chunks

Molecular weight: 193.114

Ref: 10-F161000

4-Nitrophthalic Anhydride

Controlled Product

CAS: 5466-84-2

Applications 5-Nitrophthalic Anhydride is used in the preparation of phthalic acids as well as compounds with anticonvulsant activities.
References Rao, K.S. et al.: Curr. Sci., 42, 124 (1973); Bailleux, V. et al.: Chem. Pharmac. Bull., 42, 1817 (1994);

Formula: C₈H₃NO₅

Color and Shape: Neat

Molecular weight: 193.113

Ref: TR-N515325