Polyguanylic acid (5') potassium, with the CAS number 54684-83-2, is a synthetic polynucleotide characterized by its polymeric structure composed of guanine nucleotides linked by phosphodiester bonds. This substance is typically found in a potassium salt form, which enhances its solubility in aqueous solutions. Polyguanylic acid is known for its ability to form stable secondary structures, such as G-quadruplexes, which can play significant roles in biological processes, including gene regulation and cellular signaling. Its unique properties make it a subject of interest in molecular biology and biochemistry, particularly in studies related to RNA and DNA interactions. Additionally, polyguanylic acid can be utilized in various applications, including as a potential therapeutic agent and in the development of nucleic acid-based technologies. The potassium salt form is particularly advantageous for laboratory use, as it provides a stable and soluble form of the polymer for experimental purposes.

polyguanylic acid (5') potassium

54684-83-2: Polyguanylic acid (5') potassium, with the CAS number 54684-83-2, is a synthetic polynucleotide characterized by its polymeric structure composed of guanine nucleotides linked by phosphodiester bonds. This substance is typically found in a potassium salt form, which enhances its solubility in aqueous solutions. Polyguanylic acid is known for its ability to form stable secondary structures, such as G-quadruplexes, which can play significant roles in biological processes, including gene regulation and cellular signaling. Its unique properties make it a subject of interest in molecular biology and biochemistry, particularly in studies related to RNA and DNA interactions. Additionally, polyguanylic acid can be utilized in various applications, including as a potential therapeutic agent and in the development of nucleic acid-based technologies. The potassium salt form is particularly advantageous for laboratory use, as it provides a stable and soluble form of the polymer for experimental purposes.

Polyguanylic acid potassium salt is a guanosine analog that is used as a probe for studying the interaction of cellular and target tissue. It has been found to be taken up by cells, with high affinity constants, and to be immobilized on cell surfaces. Polyguanylic acid potassium salt can also be used as an anticancer agent against epidermoid carcinoma cells with high affinity constants. The compound interacts with DNA and inhibits the growth of the tumor cells by interfering with the uptake of nucleic acids.

CAS 54684-83-2

polyguanylic acid (5') potassium

Polyguanylic acid potassium

Ref: 3D-NP44590