CAS 547-75-1
:Hyocholic acid
Description:
Hyocholic acid, with the CAS number 547-75-1, is a bile acid that is derived from cholesterol and is primarily found in the bile of certain animals, particularly in the intestines of some mammals. It is characterized by its steroid structure, which consists of a four-ring core with various functional groups that contribute to its amphipathic nature, allowing it to interact with both lipophilic and hydrophilic environments. Hyocholic acid plays a significant role in the digestion and absorption of dietary fats and fat-soluble vitamins by emulsifying lipids in the intestinal tract. Its solubility properties facilitate the formation of micelles, which are essential for the efficient uptake of lipids. Additionally, hyocholic acid can influence cholesterol metabolism and has been studied for its potential effects on lipid profiles and metabolic health. As a bile acid, it also participates in enterohepatic circulation, where it is reabsorbed in the intestine and returned to the liver. Overall, hyocholic acid is an important biochemical compound with implications in digestion and metabolism.
Formula:C24H40O5
InChI:InChI=1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15-,16+,17+,18+,20+,21-,22+,23-,24-/m1/s1
InChI key:InChIKey=DKPMWHFRUGMUKF-KWXDGCAGSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])([C@H](O)[C@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]
Synonyms:- (3α,5β,6α,7α)-3,6,7-Trihydroxycholan-24-oic acid
- 3,6,12-Trihydroxycholan-24-oic acid
- 3alpha,6alpha,7alpha-Trihydroxy-5beta-cholan-24-oic acid
- 3α,6α,7α-Trihydroxy-5β-cholanic acid
- 3α,6α,7α-Trihydroxy-5β-cholanoic acid
- 5β-Cholan-24-oic acid, 3α,6α,7α-trihydroxy-
- 5β-Cholanic acid, 3α,6α,7α-trihydroxy-
- 5β-Cholanic acid-3α,6α,7α-triol
- 6α-Hydroxychenodeoxycholic acid
- Cholan-24-oic acid, 3,6,7-trihydroxy-, (3alpha,5beta,6alpha,7alpha)-
- Cholan-24-oic acid, 3,6,7-trihydroxy-, (3α,5β,6α,7α)-
- Hyocholic acid
- Iocholic acid
- α-Hyocholic acid
- See more synonyms
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Found 8 products.
Hyocholic acid
CAS:<p>Hyocholic acid is a natural product for research related to life sciences. The catalog number is TN7024 and the CAS number is 547-75-1.</p>Formula:C24H40O5Purity:99.60%Color and Shape:SolidMolecular weight:408.57Hyocholic acid
CAS:Controlled Product<p>Hyocholic acid is a bile acid that is a natural compound that has been shown to have cholesterol-lowering effects. It has been shown to inhibit hepatic steatosis and congestive heart failure, as well as bind to the receptor for bile acids, which may lead to physiological effects. The physiological levels of hyocholic acid in the human serum are unknown, but it has been shown to inhibit the activities of hyocholic acid hydrolase and cholesterol 7 alpha-hydroxylase in vitro. This inhibition leads to an accumulation of bile acids and cholesterol in the liver and blood and induces a condition known as hypercholesterolemia.</p>Formula:C24H40O5Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:408.57 g/mol3α,6α,7α-Trihydroxy-5β-cholanic Acid
CAS:Controlled Product<p>Applications 3α,6α,7α-Trihydroxy-5β-cholanic Acid is one of the bile acids categorizes under muricholic acid, a group of bile acids found in human urine due to its additional hydroxyl groups. The synthesis of 3α,6α,7α-Trihydroxy-5β-cholanic Acid was shown to be promoted due to overexpression of cholesterol 7α-hydroxylase enzyme.<br>References Debray, D., et al.: Gastroenterol., 142, 1581 (2012); Li, T.G., et al.: Hepatol., 53, 996 (2011);<br></p>Formula:C24H40O5Color and Shape:NeatMolecular weight:408.571
