CAS 547-81-9

16-epiestriol

Description:

16-Epiestriol is a naturally occurring steroid and a derivative of estriol, which is a type of estrogen. It is characterized by its molecular structure, which includes a steroid backbone with specific functional groups that contribute to its biological activity. This compound is primarily known for its role in the endocrine system, particularly in relation to female reproductive health. It exhibits estrogenic activity, influencing various physiological processes such as menstrual cycle regulation and reproductive system function. The chemical formula of 16-epiestriol reflects its composition of carbon, hydrogen, and oxygen atoms, typical of steroid hormones. Its CAS number, 547-81-9, is a unique identifier used to facilitate the identification of this substance in chemical databases. In research and clinical settings, 16-epiestriol may be studied for its potential therapeutic applications, particularly in hormone replacement therapies and in understanding estrogen-related conditions. However, as with all hormones, its effects can vary based on dosage and individual biological responses.

Formula: C₁₈H₂₄O₃

InChI: InChI=1/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16+,17+,18+/m1/s1

InChI key: InChIKey=PROQIPRRNZUXQM-ZMSHIADSSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(C[C@H](O)[C@@H]2O)[H]

Synonyms:

• (16Beta,17Beta)-Estra-1,3,5(10)-Triene-3,16,17-Triol
• (16β,17β)-Estra-1,3,5(10)-triene-3,16,17-triol
• 16-Epiestratriol
• 16-epi-Estriol
• 16β,17β-Estriol
• 16β-Hydroxyestradiol
• Actriol
• Epiestriol
• Epioestriol
• Estra-1,3,5(10)-triene-3,16,17-triol, (16β,17β)-
• Estra-1,3,5(10)-triene-3,16β,17-triol
• Estra-1,3,5(10)-triene-3,16β,17β-triol
• NSC 26646
• 16-Epiestriol
• Estriol IMpurity F
• 1,3,5(10)-ESTRATRIEN-3,16B,17B-TRIOL
• 16β-Oestriol
• Estra-1,3,5(10)-triene-3,16beta,17beta-triol
• EPIESTRIOL, 16-
• 16-EPISTRIOL
• 16beta,17beta-Estriol
• 1,3,5[10]-ESTRATRIENE-3,16BETA,17BETA-TRIOL
• EPIESTRIOL, 16-(RG)
• 16BETA-HYDROXY-17BETA-ESTRADIOL
• 16-epioestriol
• Estra-1,3,5(10)-triene-3,16,17-triol, (16beta,17beta)-
• (16,17)-Estra-1,3,5(10)-triene-3,16,17-triol
• 3,16beta,17beta-Estriol
• 16BETA-HYDROXYESTRADIOL
• (8R,9S,13S,14S,16S,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol
• 3,16BETA,17BETA-TRIHYDROXY-1,3,5[10]-ESTRATRIENE
• Conjugated Estrogens EP Impurity F
• 5(10)-triene-3,16,17-triol,(16beta,17beta)-estra-3
• 1,3,5(10)-ESTRATRIEN-3,16-BETA, 17-BETA-TRIOL

Estriol impurity standard

CAS: 547-81-9

Estriol impurity standard

Color and Shape: Off-White

Ref: 47-753

Estriol EP Impurity F

CAS: 547-81-9

Formula: C₁₈H₂₄O₃

Color and Shape: White To Off-White Solid

Molecular weight: 288.39

Ref: 4Z-E-355

16-Epiestriol

CAS: 547-81-9

16-Epiestriol

Purity: 98%

Molecular weight: 288.38g/mol

Ref: 54-OR1075646

16-Epiestriol

CAS: 547-81-9

Formula: C₁₈H₂₄O₃

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 288.38

Ref: 7W-GL1600

Estra-1,3,5(10)-triene-3,16β,17β-triol (16-epi-Estriol)

Controlled Product

CAS: 547-81-9

Formula: C₁₈H₂₄O₃

Color and Shape: Neat

Molecular weight: 288.38

Ref: 86-MM0130.04

Actriol

CAS: 547-81-9

Actriol (Epiestriol) is always used as Glucocorticoid Receptor agonist.

Formula: C₁₈H₂₄O₃

Purity: 95.35% - 98.86%

Color and Shape: Solid

Molecular weight: 288.38

Ref: TM-T1683

16-Epiestriol, Ultra Pure (contains less than 0.3% Estriol)

Controlled Product

CAS: 547-81-9

Formula: C₁₈H₂₄O₃

Color and Shape: Neat

Molecular weight: 288.38

Ref: TR-E586501

16-Epiestriol

Controlled Product

CAS: 547-81-9

Impurity Estriol EP Impurity F
Applications 16-Epiestriol (Estriol EP Impurity F) is a metabolite of Estradiol.
References Marrian, B., et al.: Biochem. J., 59, 136 (1955), Dietel, M., et al.: Cancer Res., 50, 6100 (1990), Schumacher, G., et al.: Clin. Cancer Res., 5, 493 (1999), Robert, J., et al.: J. Med. Chem., 46, 4805 (2003),

Formula: C₁₈H₂₄O₃

Color and Shape: White

Molecular weight: 288.38

Ref: TR-E586500

16-Epiestriol

Controlled Product

CAS: 547-81-9

16-Epiestriol is a natural estrogen that can be found in urine samples. It has been shown to bind to the glucocorticoid receptor, which plays an important role in the regulation of immune responses and metabolism. 16-Epiestriol has also been shown to have immunosuppressive activities and may be used to treat cancer. 16-Epiestriol is metabolized by esterases in the liver, which leads to the production of covalent adducts. These covalent adducts bind to proteins in human liver and other tissues, leading to potential carcinogenicity. 16-Epiestriol binds with high affinity to streptococcus faecalis, which is an opportunistic pathogen associated with urinary tract infections. The optimum pH for this drug is 8.5 and it has been shown that it does not bind well at pH levels below 7 or above 11.

Formula: C₁₈H₂₄O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 288.38 g/mol

Ref: 3D-FE22724

Estriol EP Impurity F

CAS: 547-81-9

Formula: C₁₈H₂₄O₃

Molecular weight: 288.4

Ref: ST-EA-CP-E28006