CAS 547-98-8

Trihydroxycoprostanic acid

Description:

Trihydroxycoprostanic acid, with the CAS number 547-98-8, is a chemical compound that belongs to the class of steroid acids. It is characterized by the presence of three hydroxyl (-OH) groups attached to its steroid backbone, which contributes to its unique chemical properties and biological activities. This compound is derived from coprostanol, a sterol that is a product of cholesterol metabolism in the human gut. The presence of multiple hydroxyl groups enhances its solubility in water compared to other steroid compounds, influencing its interactions in biological systems. Trihydroxycoprostanic acid may play a role in various physiological processes, including lipid metabolism and signaling pathways. Its structural features allow it to participate in hydrogen bonding, which can affect its reactivity and interactions with other biomolecules. While specific applications and biological functions may vary, compounds like trihydroxycoprostanic acid are of interest in biochemistry and pharmacology for their potential roles in health and disease.

Formula: C₂₇H₄₆O₅

InChI: InChI=1/C27H46O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h15-24,28-30H,5-14H2,1-4H3,(H,31,32)/t15-,16?,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1

InChI key: InChIKey=CNWPIIOQKZNXBB-VCVMUKOKSA-N

SMILES: O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCCC(C(O)=O)C)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]

Synonyms:

• (3α,5β,7α,12α)-3,7,12-Trihydroxycholestan-26-oic acid
• 3α,7α,12α-Trihydroxy-5β-cholestan-26-oic acid
• 3α,7α,12α-Trihydroxycoprostanic acid
• 5β-Cholestan-26-oic acid, 3α,7α,12α-trihydroxy-
• 5β-Cholestane-3α,7α,12α-triol-26-oic acid
• 72879-22-2
• Cholestan-26-oic acid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)-
• Coprocholic acid
• Dec-2-Enedioic Acid
• Trihydroxycoprostanic acid
• Trihydroxycoprostanoic acid
• 3,7,12-trihydroxycholestan-26-oic acid
• THCA
• 3α,7α,12α-Trihydroxy-5β-cholestanoic acid
• Trihydroxycholestanoic acid
• 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid
• 3α,7α,12α-Trihydroxycoprostanoic acid
• (3a,5b,7a,12a)-3,7,12-trihydroxy-Cholestan-26-oic acid
• 3α,7α,12α-Trihydroxy-5β-cholestan-27-oic acid
• cholestan-26-oic acid, 3,7,12-trihydroxy-, (3alpha,5beta,7alpha,8xi,12alpha)-

Trihydroxycholestanoic Acid

CAS: 547-98-8

Trihydroxycholestanoic acid aids cholic acid creation; high levels indicate Zellweger syndrome due to faulty PEX genes.

Formula: C₂₇H₄₆O₅

Color and Shape: Solid

Molecular weight: 450.66

Ref: TM-T37666

Trihydroxycoprostanic Acid (Mixture of Diastereomers)

CAS: 547-98-8

Formula: C₂₇H₄₆O₅

Color and Shape: White To Off-White Solid

Molecular weight: 450.66

Ref: 4Z-C-5757

3a,7a,12a-Trihydroxy-5b-cholestan-26-oic acid

CAS: 547-98-8

Formula: C27H46O5

Purity: >95%

Color and Shape: Solid

Molecular weight: 450.65

Ref: 48-65-1108

3,7,12-Trihydroxycoprostanoic acid

CAS: 547-98-8

Formula: C27H46O5

Purity: >98%

Color and Shape: Solid

Molecular weight: 450.65

Ref: 48-65-1050

3alpha,7alpha,12alpha-Trihydroxycoprostanic Acid

Controlled Product

CAS: 547-98-8

Formula: C₂₇H₄₆O₅

Color and Shape: Neat

Molecular weight: 450.65

Ref: TR-T795155

3,7,12-Trihydroxycoprostanoic acid

Controlled Product

CAS: 547-98-8

3,7,12-Trihydroxycoprostanoic acid (TRHCA) is a fatty acid that is a product of the oxidation of cholestane. It has been shown to inhibit the viral replication of hepatitis B virus in human liver cells by inhibiting the atp-dependent transport. The conversion of TRHCA to cholic acid is an important step in the metabolism of cholesterol and bile acids. The enzyme cytochrome P450 2C8 metabolizes TRHCA into cholic acid. This enzyme is found primarily in the liver cells and catalyzes this reaction with a high affinity for TRHCA.
TRHCA has also been shown to have anti-inflammatory properties due to its ability to reduce prostaglandin synthesis.

Formula: C₂₇H₄₆O₅

Purity: Min. 95%

Molecular weight: 450.7 g/mol

Ref: 3D-AAA54798

3α,7α,12α-Trihydroxycoprostanic Acid

CAS: 547-98-8

Formula: C₂₇H₄₆O₅

Molecular weight: 450.65

Ref: ST-EA-CP-C93041