CAS 5472-46-8

ethyl 4-amino-2-methylpyrimidine-5-carboxylate

Description:

Ethyl 4-amino-2-methylpyrimidine-5-carboxylate, with the CAS number 5472-46-8, is an organic compound that belongs to the class of pyrimidine derivatives. This substance features a pyrimidine ring substituted with an amino group at the 4-position and a carboxylate ester at the 5-position, along with a methyl group at the 2-position. The presence of the ethyl ester group contributes to its solubility in organic solvents, making it useful in various chemical reactions. The compound is typically characterized by its crystalline solid form and exhibits properties such as moderate stability under standard conditions. It may participate in various chemical reactions, including nucleophilic substitutions and condensation reactions, due to the functional groups present. Ethyl 4-amino-2-methylpyrimidine-5-carboxylate is of interest in medicinal chemistry and may serve as a precursor for the synthesis of biologically active compounds. Safety data should be consulted for handling and storage, as with any chemical substance.

Formula: C₈H₁₁N₃O₂

InChI: InChI=1/C8H11N3O2/c1-3-13-8(12)6-4-10-5(2)11-7(6)9/h4H,3H2,1-2H3,(H2,9,10,11)

SMILES: CCOC(=O)c1cnc(C)[nH]c1=N

Synonyms:

• 5-Pyrimidinecarboxylic Acid, 4-Amino-2-Methyl-, Ethyl Ester
• Ethyl 4-amino-2-methylpyrimidine-5-carboxylate

Ethyl 4-amino-2-methylpyrimidine-5-carboxylate

CAS: 5472-46-8

Formula: C₈H₁₁N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 181.1918

Ref: IN-DA00DILZ

Ethyl 4-amino-2-methylpyrimidine-5-carboxylate

CAS: 5472-46-8

Ethyl 4-amino-2-methylpyrimidine-5-carboxylate

Purity: 98%

Molecular weight: 181.19g/mol

Ref: 54-OR76093

Ethyl 4-Amino-2-methylpyrimidine-5-carboxylate

CAS: 5472-46-8

Formula: C₈H₁₁N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 181.195

Ref: 10-F067004

Ethyl 4-Amino-2-methylpyrimidine-5-carboxylate

CAS: 5472-46-8

Ethyl 4-amino-2-methylpyrimidine-5-carboxylate is a synthetic, nonsteroidal androgen receptor antagonist. It binds to the androgen receptor in prostate cancer cells, which inhibits the function of this receptor and prevents testosterone from activating it. This drug has been shown to have anticancer activity in human lung cancer and human prostate cancer, as well as other cancers. Ethyl 4-amino-2-methylpyrimidine-5-carboxylate is also able to cross the blood brain barrier and inhibit tumor growth in the brain. Human lung tumors are sensitive to this drug at concentrations of 10 μM or higher. The mechanism of action for this drug involves binding to the DNA in tumor cells, inhibiting transcription of genes that regulate cell growth and proliferation. Ethyl 4-amino-2-methylpyrimidine-5 carboxylate has been shown to be effective against tautomeric forms of benzene including

Formula: C₈H₁₁N₃O₂

Purity: Min. 95%

Molecular weight: 181.2 g/mol

Ref: 3D-FAA47246