CAS 54734-85-9
:2-Amino-5-nitrobenzenesulfonamide
Description:
2-Amino-5-nitrobenzenesulfonamide, also known as sulfanilamide, is an organic compound characterized by the presence of an amino group, a nitro group, and a sulfonamide functional group attached to a benzene ring. This compound typically appears as a crystalline solid and is soluble in water, which is a notable feature for many sulfonamide derivatives. Its molecular structure contributes to its properties, including its ability to act as a competitive inhibitor of bacterial dihydropteroate synthase, making it relevant in the field of antimicrobial agents. The nitro group enhances its reactivity and potential for further chemical modifications. Additionally, 2-amino-5-nitrobenzenesulfonamide can exhibit various biological activities, including antibacterial and anti-inflammatory effects. Safety considerations are important, as with many sulfonamides, due to potential allergic reactions in sensitive individuals. Overall, this compound serves as a significant example of sulfonamide chemistry with applications in pharmaceuticals and medicinal chemistry.
Formula:C6H7N3O4S
InChI:InChI=1S/C6H7N3O4S/c7-5-2-1-4(9(10)11)3-6(5)14(8,12)13/h1-3H,7H2,(H2,8,12,13)
InChI key:InChIKey=SKATTZSUUSDLRS-UHFFFAOYSA-N
SMILES:S(N)(=O)(=O)C1=CC(N(=O)=O)=CC=C1N
Synonyms:- 2-Amino-5-nitrobenzenesulfonamide
- 2-Amino-5-nitrobenzenesulphonamide
- 2-Amino-5-nitrobenzene-1-sulfonamide
- Benzenesulfonamide, 2-amino-5-nitro-
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Found 2 products.
2-Amino-5-nitrobenzenesulfonamide
CAS:<p>2-Amino-5-nitrobenzenesulfonamide is a synthetic compound that is an inhibitor of the NS5B polymerase enzyme, which is part of the hepatitis C virus (HCV). It has been shown to be active against genotype 1 HCV. The chemical structure of 2-amino-5-nitrobenzenesulfonamide is similar to that of other unsymmetrical dialkyl sulfonamides, and it is classified as a class I NS5B polymerase inhibitor. 2-Amino-5-nitrobenzenesulfonamide can inhibit viral replication in vitro by inhibiting the activity of the HCV NS5B polymerase enzyme. It has also been shown to be effective against genotype 4 HCV in mice. In addition, this drug inhibits alkane biosynthesis in bacteria through competitive inhibition with a natural substrate (2-aminobenzothiazole) and analogs have been</p>Formula:C6H7N3O4SPurity:Min. 95%Molecular weight:217.2 g/mol
