CAS 548-66-3

Drofenine hydrochloride

Description:

Drofenine hydrochloride is a chemical compound primarily recognized for its analgesic and anti-inflammatory properties. It is classified as a non-steroidal anti-inflammatory drug (NSAID) and is often utilized in the treatment of pain and inflammation associated with various conditions. The compound is characterized by its ability to inhibit the synthesis of prostaglandins, which are mediators of pain and inflammation in the body. Drofenine hydrochloride is typically administered in oral form and is known for its relatively rapid onset of action. In terms of its chemical structure, it features a phenyl group and a carboxylic acid moiety, contributing to its pharmacological activity. The hydrochloride salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. As with many medications, potential side effects may include gastrointestinal discomfort, allergic reactions, or interactions with other drugs, necessitating careful consideration during use. Overall, Drofenine hydrochloride serves as an important therapeutic agent in managing pain and inflammation.

Formula: C₂₀H₃₁NO₂·ClH

InChI: InChI=1S/C20H31NO2.ClH/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5,7-8,11-12,18-19H,3-4,6,9-10,13-16H2,1-2H3;1H

InChI key: InChIKey=WIELVDXKOYPANK-UHFFFAOYSA-N

SMILES: C(C(OCCN(CC)CC)=O)(C1CCCCC1)C2=CC=CC=C2.Cl

Synonyms:

• 2-(2-Cyclohexyl-2-Phenylacetoxy)Ethyldiethylammonium Chloride
• 2-(Diethylamino)Ethyl Cyclohexyl(Phenyl)Acetate Hydrochloride (1:1)
• 2-(Diethylamino)ethyl 2-cyclohexyl-2-phenylacetate hydrochloride
• 2-(Diethylamino)ethyl α-cyclohexylbenzeneacetate hydrochloride
• 2-Diethylaminoethyl Alpha-Cyclohexylphenylacetate Hydrochloride
• Adiphenine H hydrochloride
• Benzeneacetic acid, α-cyclohexyl-, 2-(diethylamino)ethyl ester, hydrochloride
• Benzeneacetic acid, α-cyclohexyl-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
• Cycloadiphenine
• Cycloadiphenine hydrochloride
• Cyclohexaneacetic acid, α-phenyl-, 2-(diethylamino)ethyl ester hydrochloride
• Cyclospasmol [Tempelhof]
• Cyclovegantine
• Hexahydroadiphenine hydrochloride
• It 19
• NSC 42559
• Trasentin H

Drofenine Hydrochloride

CAS: 548-66-3

Color and Shape: Neat

Ref: 61-FOR0768.00

Drofenine hydrochloride

CAS: 548-66-3

Drofenine hydrochloride (Hexahydroadiphenine hydrochloride) is an effective competitive inhibitor of BChE (Ki value: 3 uM).

Formula: C₂₀H₃₁NO₂·HCl

Purity: 99.45%

Color and Shape: Solid

Molecular weight: 353.93

Ref: TM-T0713

Drofenine hydrochloride

CAS: 548-66-3

Drofenine hydrochloride

Purity: ≥98%

Molecular weight: 353.93g/mol

Ref: 54-BUP11704

Drofenine Hydrochloride

Controlled Product

CAS: 548-66-3

Formula: C₂₀H₃₁NO₂·ClH

Color and Shape: Neat

Molecular weight: 353.93

Ref: 86-MM0768.00

DROFENINE HYDROCHLORIDE

CAS: 548-66-3

Purity: ≥96%

Molecular weight: 353.9299927

Ref: 10-F866547

Drofenine Hydrochloride-d4

Controlled Product

CAS: 548-66-3

Formula: C₂₀D₄H₂₇NO₂·HCl

Color and Shape: Neat

Molecular weight: 357.951

Ref: TR-D679002

Drofenine Hydrochloride

Controlled Product

CAS: 548-66-3

Applications Drofenine is a widely used anticholinergic drug. It acts on smooth muscle to stop muscle spasms.
References Ebru, B., et al.: Arch. Biochem. Biophys., 1, 25 (2001)

Formula: C₂₀H₃₁NO₂·ClH

Color and Shape: Neat

Molecular weight: 353.93

Ref: TR-D679000