CAS 548-73-2
:Droperidol
Description:
Droperidol is an antipsychotic and antiemetic medication primarily used in the management of nausea and vomiting, particularly in surgical and postoperative settings. It belongs to the butyrophenone class of compounds and acts as a dopamine antagonist, specifically targeting D2 receptors in the central nervous system. Droperidol is characterized by its ability to induce sedation and reduce anxiety, making it useful in preoperative settings. The substance is typically administered via injection and has a relatively rapid onset of action. Its chemical structure includes a butyrophenone moiety, contributing to its pharmacological properties. While effective, droperidol has been associated with potential side effects, including sedation, hypotension, and, in rare cases, serious cardiac effects such as QT prolongation. Due to these risks, its use has become more cautious, and it is often reserved for specific clinical scenarios. Overall, droperidol remains a valuable tool in anesthetic practice, balancing efficacy with careful monitoring of patient safety.
Formula:C22H22FN3O2
InChI:InChI=1/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)
InChI key:InChIKey=RMEDXOLNCUSCGS-UHFFFAOYSA-N
SMILES:O=C1N(C=2C(N1)=CC=CC2)C=3CCN(CCCC(=O)C4=CC=C(F)C=C4)CC3
Synonyms:- 1-(1-[4-(p-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone
- 1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone
- 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one
- 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one
- 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
- 2-Benzimidazolinone, 1-[1-[3-(p-fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-
- 2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-
- 3-(1-(3-(4-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-1H-benzimidazol-2-one
- Dehydrobenzperidol
- Dridol
- Droleptan
- Inapsin
- Inapsine
- Inopsin
- McN-JR 4749
- Neurolidol
- Nsc 169874
- R 4749
- Sintodril
- 1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazo
- 1-(1-[4-FLUOROBENZOYLPROPYL]-1,2,3,6-TETRAHYDRO-4-PYRIDYL)-2-BENZIMIDAZOLINONE
- 1-(4-Fluorophenyl)-4-(4-(2-hydroxy-1H-benzimidazol-1-yl)-3,6-dihydro-1(2H)-pyridinyl)-1-butanone
- 1-(1-(4-(p-fluorophenyl-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidaz
- component of Innovar
- 2-benzimidazolinone,1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyri
- 1-[1-(P-FLUOROBENZOYLPROPYL)-1,2,3,6-TETRAHYDRO-4-PYRIDYL]-2-BENZIMIDAZOLINONE
- 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-2h-benzimidazol-2-on
- 3-dihydro-4-pyridinyl)-
- 1-(1-(4-(p-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimi
- DROPERIDOL
- Deidrobenzperidolo
- Dehidrobenzperidol
- See more synonyms
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Found 18 products.
Droperidol
CAS:DroperidolFormula:C22H22FN3O2Purity:99.3%Color and Shape:White To BeigeMolecular weight:379.16961Droperidol
CAS:Clozapine; droperidol; and imipramine hydrochloridFormula:C22H22FN3O2Color and Shape:PowderMolecular weight:379.16961Droperidol
CAS:<p>Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.</p>Formula:C22H22FN3O2Purity:97.16% - 98%Color and Shape:SolidMolecular weight:379.43Droperidol
CAS:Formula:C22H22FN3O2Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:379.43Droperidol
CAS:Controlled Product<p>Applications A D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic. Neuroprotective agent.<br>References Yelnosky, J., et al.: Toxicol. Appl. Pharmacol., 6, 37 (1964), Janicki, C.A., et al.: Anal. Profiles Drug Subs., 7, 171 (1978), Hamik, et al.: Cancer Chemother. Pharmacol., 24, 307 (1989), Heyer, E.J., et al.: Brain Res., 863, 20 (2000),<br></p>Formula:C22H22FN3O2Color and Shape:NeatMolecular weight:379.43Droperidol
CAS:Controlled Product<p>Droperidol is a butyrophenone derivative, which is an antipsychotic agent and antiemetic medication, sourced from synthetic chemical processes. Its mode of action involves antagonism of dopamine D2 receptors in the central nervous system, particularly in the chemoreceptor trigger zone of the brain, and it also possesses some alpha-adrenergic blocking properties.</p>Formula:C22H22FN3O2Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:379.43 g/mol
