CAS 548-73-2

Droperidol

Description:

Droperidol is an antipsychotic and antiemetic medication primarily used in the management of nausea and vomiting, particularly in surgical and postoperative settings. It belongs to the butyrophenone class of compounds and acts as a dopamine antagonist, specifically targeting D2 receptors in the central nervous system. Droperidol is characterized by its ability to induce sedation and reduce anxiety, making it useful in preoperative settings. The substance is typically administered via injection and has a relatively rapid onset of action. Its chemical structure includes a butyrophenone moiety, contributing to its pharmacological properties. While effective, droperidol has been associated with potential side effects, including sedation, hypotension, and, in rare cases, serious cardiac effects such as QT prolongation. Due to these risks, its use has become more cautious, and it is often reserved for specific clinical scenarios. Overall, droperidol remains a valuable tool in anesthetic practice, balancing efficacy with careful monitoring of patient safety.

Formula: C₂₂H₂₂FN₃O₂

InChI: InChI=1/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)

InChI key: InChIKey=RMEDXOLNCUSCGS-UHFFFAOYSA-N

SMILES: O=C1N(C=2C(N1)=CC=CC2)C=3CCN(CCCC(=O)C4=CC=C(F)C=C4)CC3

Synonyms:

• 1-(1-[4-(p-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone
• 1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone
• 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one
• 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one
• 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
• 2-Benzimidazolinone, 1-[1-[3-(p-fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-
• 2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-
• 3-(1-(3-(4-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-1H-benzimidazol-2-one
• Dehydrobenzperidol
• Dridol
• Droleptan
• Inapsin
• Inapsine
• Inopsin
• McN-JR 4749
• Neurolidol
• Nsc 169874
• R 4749
• Sintodril
• 1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazo
• 1-(1-[4-FLUOROBENZOYLPROPYL]-1,2,3,6-TETRAHYDRO-4-PYRIDYL)-2-BENZIMIDAZOLINONE
• 1-(4-Fluorophenyl)-4-(4-(2-hydroxy-1H-benzimidazol-1-yl)-3,6-dihydro-1(2H)-pyridinyl)-1-butanone
• 1-(1-(4-(p-fluorophenyl-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidaz
• component of Innovar
• 2-benzimidazolinone,1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyri
• 1-[1-(P-FLUOROBENZOYLPROPYL)-1,2,3,6-TETRAHYDRO-4-PYRIDYL]-2-BENZIMIDAZOLINONE
• 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-2h-benzimidazol-2-on
• 3-dihydro-4-pyridinyl)-
• 1-(1-(4-(p-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimi
• DROPERIDOL
• Deidrobenzperidolo
• Dehidrobenzperidol

Droperidol

Controlled Product

CAS: 548-73-2

Droperidol is a butyrophenone derivative, which is an antipsychotic agent and antiemetic medication, sourced from synthetic chemical processes. Its mode of action involves antagonism of dopamine D2 receptors in the central nervous system, particularly in the chemoreceptor trigger zone of the brain, and it also possesses some alpha-adrenergic blocking properties.

Formula: C₂₂H₂₂FN₃O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 379.43 g/mol

Ref: 3D-FF22616

Droperidol

CAS: 548-73-2

Formula: C₂₂H₂₂FN₃O₂

Color and Shape: Solid

Molecular weight: 379.4

Ref: BE-MU-5305

Droperidol

CAS: 548-73-2

Formula: C₂₂H₂₂FN₃O₂

Color and Shape: Solid

Molecular weight: 379.4

Ref: BE-BePure-22502

Droperidol

CAS: 548-73-2

Formula: C₂₂H₂₂FN₃O₂

Color and Shape: Solid

Molecular weight: 379.4

Ref: BE-RMCD238000