CAS 548-90-3

Trichodesmine

Description:

Trichodesmine, with the CAS number 548-90-3, is an alkaloid compound primarily derived from certain plant species, particularly those in the family Apocynaceae. It is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its biological activity. Trichodesmine is known for its potential pharmacological properties, including effects on the central nervous system and its use in traditional medicine. The compound exhibits moderate solubility in organic solvents, while its solubility in water is limited. Its stability can be influenced by environmental factors such as pH and temperature. Trichodesmine has garnered interest in research for its potential therapeutic applications, although further studies are necessary to fully understand its mechanisms of action and safety profile. As with many alkaloids, it may also exhibit toxicity at certain concentrations, necessitating careful handling and usage in laboratory and medicinal contexts.

Formula: C₁₈H₂₇NO₆

InChI: InChI=1S/C18H27NO6/c1-10(2)13-15(20)25-12-6-8-19-7-5-11(14(12)19)9-24-16(21)18(4,23)17(13,3)22/h5,10,12-14,22-23H,6-9H2,1-4H3/t12-,13+,14-,17-,18+/m1/s1

InChI key: InChIKey=SOODLZHDDSGRKL-FOOXYVKASA-N

SMILES: O=C1O[C@]2([C@@]3(N(CC2)CC=C3COC(=O)[C@](C)(O)[C@](C)(O)[C@H]1C(C)C)[H])[H]

Synonyms:

• 2H-[1,6]Dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione, 4,5,8,10,12,13,13a,13b-decahydro-4,5-dihydroxy-4,5-dimethyl-3-(1-methylethyl)-, [3R-(3R*,4R*,5R*,13aR*,13bR*)]-
• (3R,4R,5R,13aR,13bR)-4,5,8,10,12,13,13a,13b-Octahydro-4,5-dihydroxy-4,5-dimethyl-3-(1-methylethyl)-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione
• Trichodesmine
• 2H-[1,6]Dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione, 4,5,8,10,12,13,13a,13b-octahydro-4,5-dihydroxy-4,5-dimethyl-3-(1-methylethyl)-, (3R,4R,5R,13aR,13bR)-
• Crotalanan-11,15-dione, 14,19-dihydro-12,13-dihydroxy-19-methyl-, (13α,14α)-

Trichodesmine

CAS: 548-90-3

Trichodesmine, a dehydropyrrolizidine alkaloid, exhibits hepatotoxic, pneumotoxic, and neurotoxic effects in vivo.

Formula: C₁₈H₂₇NO₆

Color and Shape: Solid

Molecular weight: 353.41

Ref: TM-T40627

Trichodesmine

CAS: 548-90-3

Formula: C₁₈H₂₇NO₆

Molecular weight: 353.42

Ref: 4Z-T-291001

Trichodesmine

CAS: 548-90-3

Natural alkaloid

Formula: C₁₈H₂₇NO₆

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 353.41

Ref: 5G-83438

Trichodesmine

Controlled Product

CAS: 548-90-3

Formula: C₁₈H₂₇NO₆

Color and Shape: Neat

Molecular weight: 353.41

Ref: TR-T774510

Trichodesmine-D4

Controlled Product

CAS: 548-90-3

Formula: C₁₈D₄H₂₃NO₆

Color and Shape: Neat

Molecular weight: 357.435

Ref: TR-T774512

Trichodesmine

CAS: 548-90-3

Trichodesmine is an analytical compound that functions as a pyrrolizidine alkaloid, which is isolated from plants belonging to the genus Crotalaria. This compound demonstrates its mode of action through the formation of toxic metabolites that interact with cellular macromolecules, leading to the disruption of normal cellular functions. The transformation of Trichodesmine into these reactive intermediates predominantly involves enzymatic oxidation facilitated by liver enzymes, specifically those in the cytochrome P450 family.

Formula: C₁₈H₂₇NO₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 353.41 g/mol

Ref: 3D-FT161629

Trichodesmine-d3

CAS: 548-90-3

Formula: C₁₈H₂₄D₃NO₆

Molecular weight: 356.43

Ref: 4Z-T-291002