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CAS 548-97-0

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6,17,21-trihydroxypregn-4-ene-3,20-dione

Description:
6,17,21-trihydroxypregn-4-ene-3,20-dione, commonly known as hydrocortisone, is a steroid hormone that plays a crucial role in various physiological processes. It is a glucocorticoid produced by the adrenal cortex and is involved in the regulation of metabolism, immune response, and stress response. This compound features three hydroxyl (-OH) groups, which contribute to its solubility and biological activity. Hydrocortisone exhibits anti-inflammatory and immunosuppressive properties, making it valuable in medical treatments for conditions such as allergies, asthma, and autoimmune disorders. Its structure includes a steroid backbone, characterized by four fused carbon rings, which is typical of steroid hormones. The presence of the double bond in the A-ring and the ketone groups at positions 3 and 20 are significant for its biological function. Hydrocortisone can be administered topically, orally, or via injection, depending on the condition being treated. Its pharmacological effects are mediated through binding to glucocorticoid receptors, influencing gene expression and cellular responses.
Formula:C21H30O5
InChI:InChI=1/C21H30O5/c1-19-6-3-12(23)9-16(19)17(24)10-13-14(19)4-7-20(2)15(13)5-8-21(20,26)18(25)11-22/h9,13-15,17,22,24,26H,3-8,10-11H2,1-2H3
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Found 2 products.
  • 6-β-Hydroxy-11-Deoxy-Hydrocortisone
    TLC
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    6-β-Hydroxy-11-Deoxy-Hydrocortisone

    CAS:
    Formula:C21H30O5
    Molecular weight:362.47

    Ref: 4Z-H-103047

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  • 6β-Hydroxy-11-deoxycortisol
    TRC
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    6β-Hydroxy-11-deoxycortisol

    Controlled Product
    CAS:

    Applications 6β-Hydroxy-11-deoxycortisol is a corticosteroid which is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids.
    References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),

    Formula:C21H30O5
    Color and Shape:Neat
    Molecular weight:362.46

    Ref: TR-H934900

    1mg
    243.00€
    5mg
    1,042.00€
    10mg
    1,676.00€