CAS 54824-17-8

Mitonafide

Description:

Mitonafide, with the CAS number 54824-17-8, is a synthetic compound that belongs to the class of benzamide derivatives. It is primarily recognized for its potential applications in the field of oncology, particularly as an antitumor agent. The chemical structure of Mitonafide features a benzamide core, which is often associated with various biological activities, including the inhibition of cell proliferation. Mitonafide has been studied for its mechanism of action, which may involve the interference with DNA synthesis or repair processes in cancer cells, leading to apoptosis. The compound is typically characterized by its moderate solubility in organic solvents and limited solubility in water, which can influence its bioavailability and pharmacokinetics. As with many pharmaceutical compounds, the safety profile, efficacy, and potential side effects of Mitonafide are critical areas of research, particularly in clinical settings. Overall, Mitonafide represents a noteworthy example of the ongoing exploration of novel therapeutic agents in cancer treatment.

Formula: C₁₆H₁₅N₃O₄

InChI: InChI=1S/C16H15N3O4/c1-17(2)6-7-18-15(20)12-5-3-4-10-8-11(19(22)23)9-13(14(10)12)16(18)21/h3-5,8-9H,6-7H2,1-2H3

InChI key: InChIKey=XXVLKDRPHSFIIB-UHFFFAOYSA-N

SMILES: O=C1C=2C=3C(C(=O)N1CCN(C)C)=CC=CC3C=C(N(=O)=O)C2

Synonyms:

• 1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-(2-(dimethylamino)ethyl)-5-nitro-
• 2-((Dimethylamino)ethyl)-2,3-dihydro-5-nitro-2-azaphenalen-1,3-dion
• 2-(2-(Dimethylamino)ethyl)-5-nitro-1H-benz(de)isoquinoline-1,3(2H)-dione
• 2-[2-(dimethylamino)ethyl]-5-nitro-1H-benzo[de]isoquinoline-1,3(2H)-dione
• 3-Nitro-N-(2-dimethylaminoethyl)-1,8-naphthalimide
• Brn 1550151
• M 4212
• M 4212 (Pharmaceutical)
• Mitonafida
• Mitonafida [INN-Spanish]
• Mitonafide [INN]
• Mitonafidum
• Mitonafidum [INN-Latin]
• N-(2-(Dimethylamino)ethyl)-3-nitronaphthalimide
• Naphthalimide, 2-(2-(dimethylamino)ethyl)-5-nitro-
• Nsc 300288

Mitonafide

CAS: 54824-17-8

Mitonafide

Purity: ≥98%

Molecular weight: 313.31g/mol

Ref: 54-BUP12296

Mitonafide

CAS: 54824-17-8

Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.

Formula: C₁₆H₁₅N₃O₄

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 313.31

Ref: TM-T25817

Mitonafide

CAS: 54824-17-8

Mitonafide is a nitro-containing, biocompatible polymer that has significant cytotoxicity. It can be used as an anti-cancer compound that induces apoptosis, or programmed cell death, of cancer cells by binding to pro-apoptotic protein. Mitonafide also inhibits the growth of infectious agents, such as bacteria and fungi. Mitonafide binds to the DNA duplexes and prevents the progression of dna synthesis in the nucleus. This drug is toxic and should not be administered without first determining if there are any interactions with other drugs that are being taken by the patient.

Formula: C₁₆H₁₅N₃O₄

Purity: Min. 95 Area-%

Color and Shape: Brown Powder

Molecular weight: 313.31 g/mol

Ref: 3D-FM26021

Mitonafide

Controlled Product

CAS: 54824-17-8

Applications A Naphthalimides with potent anticancer activity.

Formula: C₁₆H₁₅N₃O₄

Color and Shape: Neat

Molecular weight: 313.31

Ref: TR-M371990