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CAS 54845-95-3

:

15(S)-HETE

Description:
15(S)-HETE, or 15-hydroxyeicosatetraenoic acid, is a bioactive lipid derived from arachidonic acid through the action of lipoxygenase enzymes. It is classified as a hydroxyeicosanoid and is known for its role in various physiological processes, including inflammation and cell signaling. This compound exhibits anti-inflammatory properties and is involved in the regulation of vascular tone and platelet aggregation. 15(S)-HETE can influence cellular responses by acting on specific receptors and modulating the production of other signaling molecules. Its structure features a hydroxyl group at the 15th carbon position of the eicosanoid backbone, which is crucial for its biological activity. Additionally, 15(S)-HETE is studied for its potential implications in various diseases, including cardiovascular disorders and cancer, due to its involvement in cell proliferation and apoptosis. As a metabolite of arachidonic acid, it is part of a complex network of lipid mediators that contribute to homeostasis and the inflammatory response.
Formula:C20H32O3
InChI:InChI=1S/C20H32O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h4-5,8-11,14,17,19,21H,2-3,6-7,12-13,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,17-14+/t19-/m0/s1
InChI key:InChIKey=JSFATNQSLKRBCI-VAEKSGALSA-N
SMILES:C(=C/C=C\C/C=C\C/C=C\CCCC(O)=O)\[C@H](CCCCC)O
Synonyms:
  • Icomucret
  • (5Z,8Z,11Z,13E,15S)-15-Hydroxyicosa-5,8,11,13-tetraenoic acid
  • Icomucret [INN]
  • 15(S)-HETE
  • 15-HETE
  • 5,8,11,13-Eicosatetraenoic acid, 15-hydroxy-, [S-(E,Z,Z,Z)]-
  • AL-12959
  • 5,8,11,13-Eicosatetraenoic acid, 15-hydroxy-, (5Z,8Z,11Z,13E,15S)-
  • 15S-Hydroxy-5,8,11,13-(Z,Z,Z,E)-eicosatetraenoic acid
  • (5Z,8Z,11Z,13E,15S)-15-Hydroxy-5,8,11,13-eicosatetraenoic acid
  • UNII-44JHK6G39Q
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