CAS 548470-11-7
:ISRIB
Description:
ISRIB, or Integrated Stress Response Inhibitor, is a small molecule known for its role in modulating the integrated stress response (ISR) in cells. It is characterized by its ability to inhibit the phosphorylation of eIF2α, a key regulator of protein synthesis during stress conditions. By doing so, ISRIB promotes cell survival and enhances cognitive function, making it of interest in neurobiology and potential therapeutic applications for neurodegenerative diseases and stress-related disorders. ISRIB has been shown to improve memory and learning in various animal models, suggesting its potential as a cognitive enhancer. The compound is typically studied in the context of cellular stress responses, protein synthesis regulation, and neuroprotection. Its chemical structure and properties facilitate its interaction with specific cellular pathways, making it a valuable tool in research aimed at understanding stress responses and developing treatments for related conditions. As with any investigational compound, further studies are necessary to fully elucidate its mechanisms of action and therapeutic potential.
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Found 4 products.
ISRIB
CAS:ISRIB is a potent and selective PERK inhibitor.Formula:C22H24Cl2N2O4Purity:97.69% - ≥95%Color and Shape:SolidMolecular weight:451.34Isrib
CAS:<p>Isrib is a sodium citrate that has been shown to inhibit the growth of an experimental bacterial strain in vitro. Isrib has also been shown to have inhibitory properties on neuronal death in vivo. This agent has pluripotent cells that are able to differentiate into any cell type, including neurons, and can be used for the treatment of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and diabetic neuropathy. Isrib has also been shown to have beneficial effects on the immune system by stimulating antibody production and regulating inflammatory responses. It is absorbed orally with high bioavailability and its pharmacokinetic properties are similar to those of other sodium citrates.</p>Formula:C22H24Cl2N2O4Purity:Min. 95%Molecular weight:451.34 g/mol
