CAS 54867-56-0

Bufrolin

Description:

Bufrolin, with the CAS number 54867-56-0, is a chemical compound that belongs to the class of bufotenidine derivatives. It is primarily recognized for its potential pharmacological properties, particularly in the context of cardiovascular and neurological research. Bufrolin exhibits a structure that is characterized by the presence of an indole ring, which is common in many biologically active compounds. The substance is known to interact with various neurotransmitter systems, potentially influencing mood and cognitive functions. Its solubility and stability can vary depending on the formulation and environmental conditions. As with many compounds in this class, bufrolin's safety profile, including toxicity and side effects, is an important consideration in its application. Research into bufrolin continues to explore its therapeutic potential, mechanisms of action, and possible applications in treating specific medical conditions. However, detailed studies and clinical trials are necessary to fully understand its efficacy and safety in humans.

Formula: C₁₈H₁₆N₂O₆

InChI: InChI=1/C18H16N2O6/c1-2-3-4-8-5-9-12(21)6-10(17(23)24)20-16(9)14-13(22)7-11(18(25)26)19-15(8)14/h5-7H,2-4H2,1H3,(H,19,22)(H,20,21)(H,23,24)(H,25,26)

SMILES: CCCCc1cc2c(cc(C(=O)O)nc2c2c(cc(C(=O)O)nc12)O)O

Synonyms:

• Bufrolin [INN:BAN]
• 6-Butyl-1,4,7,10-tetrahydro-4,10-dioxo-1,7-phenanthroline-2,8-dicarbonsaeure
• Bufroline
• Bufroline [INN-French]
• Bufrolino
• Bufrolino [INN-Spanish]
• Bufrolinum
• Bufrolinum [INN-Latin]
• Unii-46C1Px266N
• 6-Butyl-1,4,7,10-tetrahydro-4,10-dioxo-1,7-phenanthroline-2,8-dicarboxylic acid
• 6-Butyl-4,10-Dioxo-1,4,7,10-Tetrahydro-1,7-Phenanthroline-2,8-Dicarboxylic Acid

Bufrolin

CAS: 54867-56-0

Bufrolin is a potent GPR35 agonist, mast cell stabilizer, and anti-inflammatory research agent.

Formula: C₁₈H₁₆N₂O₆

Color and Shape: Solid

Molecular weight: 356.33

Ref: TM-T73665

Bufrolin

Controlled Product

CAS: 54867-56-0

Applications Bufrolin is an analog of Sodium Cromoglycate (C815000). It is a mast cell stabilizer drug and is shown to display agonism at either human or rat G protein-coupled receptor GPR35.
References Church, Martin K., et al.: Int. Arch. Aller. A. Imm., 66, 281-2 (1981); MacKenzie Amanda E., et al.: Mol. Pharmacol., 85(1), 91-104 (2014)

Formula: C₁₈H₁₆N₂O₆

Color and Shape: Neat

Molecular weight: 356.33

Ref: TR-B689405

Bufrolin-d9

Controlled Product

CAS: 54867-56-0

Formula: C₁₈D₉H₇N₂O₆

Color and Shape: Neat

Molecular weight: 365.385

Ref: TR-B689407