Cytochalasins are a group of fungal metabolites known for their ability to disrupt cytoskeletal functions, particularly affecting actin filaments. The specific compound with the CAS number 54874-57-6 is cytochalasine D, which is derived from the fungus *Helminthosporium* species. This compound is characterized by its ability to inhibit cell division and motility by preventing the polymerization of actin, leading to significant effects on cellular processes such as cytokinesis and cell shape maintenance. Cytochalasins are often used in research to study cell biology, particularly in experiments involving cell movement, morphology, and the mechanisms of cell division. Additionally, they exhibit potential applications in cancer research due to their effects on cell proliferation. However, their use must be approached with caution, as they can also induce cytotoxicity in various cell types. Overall, cytochalasins serve as valuable tools in understanding the dynamics of the cytoskeleton and its role in cellular functions.

CYTOCHALASING

54874-57-6: Cytochalasins are a group of fungal metabolites known for their ability to disrupt cytoskeletal functions, particularly affecting actin filaments. The specific compound with the CAS number 54874-57-6 is cytochalasine D, which is derived from the fungus *Helminthosporium* species. This compound is characterized by its ability to inhibit cell division and motility by preventing the polymerization of actin, leading to significant effects on cellular processes such as cytokinesis and cell shape maintenance. Cytochalasins are often used in research to study cell biology, particularly in experiments involving cell movement, morphology, and the mechanisms of cell division. Additionally, they exhibit potential applications in cancer research due to their effects on cell proliferation. However, their use must be approached with caution, as they can also induce cytotoxicity in various cell types. Overall, cytochalasins serve as valuable tools in understanding the dynamics of the cytoskeleton and its role in cellular functions.

<p>Cytochalasin G exhibits reversible inhibition of cytokinesis and also inhibits macrophage phagocytosis and exocytosis, among other biological activities.</p>

CAS 54874-57-6

CYTOCHALASING

Cytochalasin G

Ref: TM-TN10188