CAS 548783-71-7

3,3,3-trideuterio-2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]butyl]phenyl]-2-(trideuteriomethyl)propanoic acid

Description:

3,3,3-Trideuterio-2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]butyl]phenyl]-2-(trideuteriomethyl)propanoic acid is a complex organic compound characterized by its multiple functional groups and isotopic labeling. The presence of deuterium atoms (indicated by "trideuterio") suggests that this compound is used in studies involving isotopic effects or tracing mechanisms in biochemical pathways. The structure includes a propanoic acid moiety, which contributes to its acidity and potential interactions with biological systems. The compound also features a piperidine ring, which is often associated with pharmacological activity, and multiple hydroxyl groups that enhance its solubility and reactivity. The diphenylmethyl group indicates potential for significant steric hindrance, influencing the compound's interaction with biological targets. Overall, this compound's unique structure and isotopic labeling make it a valuable tool in medicinal chemistry and pharmacokinetics, particularly in understanding drug metabolism and interactions.

Formula: C₃₂H₃₃D₆NO₄

InChI: InChI=1/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)/i1D3,2D3

SMILES: C(C(C([2H])([2H])[2H])(c1ccc(cc1)C(CCCN1CCC(CC1)C(c1ccccc1)(c1ccccc1)O)O)C(=O)O)([2H])([2H])[2H]

Synonyms:

• Carboxyterfenadine-d6
• MDL 16455-d6
• Terfenadine-d6 Carboxylate
• 4-[4-[4-(HydroxydiphenylMethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-
• 4-[1-Hydroxy-4-[4-(hydroxydiphenylMethyl)-1-piperidinyl]butyl]-α,α-(diMethyl-d6)benzeneacetic Acid
• (diMethyl-d6)phenylacetic Acid
• Terfenadine-d6 Acid Metabolite

Fexofenadine-d6

CAS: 548783-71-7

Fexofenadine D6 is an antihistamine pharmaceutical drug.Fexofenadine D6 is deuterium labeled is Fexofenadine.

Formula: C₃₂H₃₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 507.69

Ref: TM-T11276

Fexofenadine-d6

Controlled Product

CAS: 548783-71-7

Stability Hygroscopic
Applications The active labelled metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.
References Garteiz, D.A., et al.: Arzneim.-Forsch., 32, 1185 (1982), Rampe, D., et al.: Mol. Pharmacol., 44, 1240 (1993), Obradovic, T., et al.: Pharm. Res., 24, 318 (2007),

Formula: C₃₂₂H₆H₃₃NO₄

Color and Shape: Off White

Molecular weight: 507.69

Ref: TR-F322500

FEXOFENADINE-D6

CAS: 548783-71-7

Formula: C₃₂H₃₃D₆NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 507.6933

Ref: IN-DA00DB8K