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CAS 54886-50-9

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11(S)-hydroxy-(5Z,8Z,12E,14Z)-*eicosatetraenoic A

Description:
11(S)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoic acid, commonly referred to as 11-HETE, is a bioactive lipid derived from arachidonic acid through the action of lipoxygenase enzymes. This compound is characterized by its polyunsaturated fatty acid structure, featuring multiple double bonds that contribute to its reactivity and biological activity. It plays a significant role in various physiological processes, including inflammation, cell signaling, and the modulation of vascular functions. 11-HETE is known to act as a signaling molecule, influencing the behavior of immune cells and contributing to the regulation of blood flow and platelet aggregation. Its presence in biological systems is often associated with the inflammatory response, and it may serve as a precursor for the synthesis of other bioactive lipids. The compound's specific stereochemistry, particularly the presence of the hydroxyl group at the 11th carbon, is crucial for its biological activity and interaction with cellular receptors. Overall, 11-HETE is an important mediator in lipid metabolism and cellular communication.
Formula:C20H32O3
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Found 2 products.
  • 11(S)-hydroxy-5(Z),8(Z),12(E),14(Z)-eicosatetraenoic acid
    Larodan
    + Info

    11(S)-hydroxy-5(Z),8(Z),12(E),14(Z)-eicosatetraenoic acid

    CAS:
    Formula:C20H32O3
    Purity:>98%
    Color and Shape:In solution, Ethanol
    Molecular weight:320.47

    Ref: 48-14-6041

    50µg
    383.00€
  • 11(S)-HETE
    Targetmol
    + Info

    11(S)-HETE

    CAS:
    11(S)-HETE, an (S) enantiomer of 11(R)-HETE and a type of oxylipin, is non-enzymatically synthesized from arachidonic acid. Compared to its counterpart, 11(S)-HETE levels are found to be elevated in both isolated human plasma and serum, as well as in LPS-stimulated isolated human plasma. Notably, patients with allergic rhinitis exhibit a decrease in 11(S)-HETE levels in their serum following one year of double-mite subcutaneous immunotherapy (DM-SCIT), correlating with an enhanced quality of life, particularly in aspects related to rhinoconjunctivitis.
    Formula:C20H32O3
    Color and Shape:Solid
    Molecular weight:320.5

    Ref: TM-T84604