CAS 549-18-8

Amitriptyline hydrochloride

Description:

Amitriptyline hydrochloride is a tricyclic antidepressant primarily used to treat major depressive disorder and certain types of chronic pain. It is characterized by its chemical formula C20H23N·HCl, indicating the presence of a hydrochloride salt. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Amitriptyline acts by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby enhancing mood and alleviating pain. Its pharmacological effects can lead to side effects, including sedation, dry mouth, and weight gain, among others. The drug is typically administered orally and is known for its relatively long half-life, which allows for once-daily dosing in many cases. Due to its potential for overdose and interactions with other medications, careful monitoring is essential during treatment. Amitriptyline hydrochloride is classified as a prescription medication and should be used under the guidance of a healthcare professional.

Formula:C₂₀H₂₃N·ClH

InChI:InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H

InChI key:InChIKey=KFYRPLNVJVHZGT-UHFFFAOYSA-N

SMILES:C(CCN(C)C)=C1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Synonyms:

1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
10,11-Dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-Δ<sup>5</sup>,γ-propylamine hydrochloride
3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
5-(3-Dimethylaminopropylidene)dibenzo[a,d][1,4]cycloheptadiene hydrochloride
5H-Dibenzo[a,d]cycloheptene-Δ<sup>5,γ</sup>-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride
Adepril
Amicen
Amil 25
Amilent
Amilit
Amineurin
Amiplin
Amiprin
Amitid
Amitril
Amitrip
Amitriptyline HCl
Amitriptyline Hcl Methanol Solution
Amitriptyline chloride
Amitriptyline hydrochloride
Amitryptilline Hcl
Amyline
Amyzol
Anapsique
Apo-Amitriptyline
Damilen hydrochloride
Deprex
Domical
Elatrol
Elatrolet
Elavil
Enafon
Endep
Etravil
Euplit
Lantron
Laroxyl
Larozyl
Lentizol
Miketorin
Nih 10794
Noriline
Novoprotect
Pinsanu
Pinsaun
Redomex
Ro 4-1575
Saroten
Saroten Retard
Sarotena
Sarotex
Sylvemid
Syneudon
Teperin
Trepiline
Tridep
Tripta
Triptizol
Trynol
Tryptal
Tryptanol
Tryptine
Tryptizol
Trytomer
Vanatrip
[3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-dimethyl-amine; hydrochloride
5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride
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