CAS 549-18-8

Amitriptyline hydrochloride

Description:

Amitriptyline hydrochloride is a tricyclic antidepressant primarily used to treat major depressive disorder and certain types of chronic pain. It is characterized by its chemical formula C20H23N·HCl, indicating the presence of a hydrochloride salt. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Amitriptyline acts by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby enhancing mood and alleviating pain. Its pharmacological effects can lead to side effects, including sedation, dry mouth, and weight gain, among others. The drug is typically administered orally and is known for its relatively long half-life, which allows for once-daily dosing in many cases. Due to its potential for overdose and interactions with other medications, careful monitoring is essential during treatment. Amitriptyline hydrochloride is classified as a prescription medication and should be used under the guidance of a healthcare professional.

Formula: C₂₀H₂₃N·ClH

InChI: InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H

InChI key: InChIKey=KFYRPLNVJVHZGT-UHFFFAOYSA-N

SMILES: C(CCN(C)C)=C1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Synonyms:

• 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride
• 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
• 10,11-Dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-Δ⁵,γ-propylamine hydrochloride
• 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
• 5-(3-Dimethylaminopropylidene)dibenzo[a,d][1,4]cycloheptadiene hydrochloride
• 5H-Dibenzo[a,d]cycloheptene-Δ^5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride
• Adepril
• Amicen
• Amil 25
• Amilent
• Amilit
• Amineurin
• Amiplin
• Amiprin
• Amitid
• Amitril
• Amitrip
• Amitriptyline HCl
• Amitriptyline Hcl Methanol Solution
• Amitriptyline chloride
• Amitriptyline hydrochloride
• Amitryptilline Hcl
• Amyline
• Amyzol
• Anapsique
• Apo-Amitriptyline
• Damilen hydrochloride
• Deprex
• Domical
• Elatrol
• Elatrolet
• Elavil
• Enafon
• Endep
• Etravil
• Euplit
• Lantron
• Laroxyl
• Larozyl
• Lentizol
• Miketorin
• Nih 10794
• Noriline
• Novoprotect
• Pinsanu
• Pinsaun
• Redomex
• Ro 4-1575
• Saroten
• Saroten Retard
• Sarotena
• Sarotex
• Sylvemid
• Syneudon
• Teperin
• Trepiline
• Tridep
• Tripta
• Triptizol
• Trynol
• Tryptal
• Tryptanol
• Tryptine
• Tryptizol
• Trytomer
• Vanatrip
• [3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-dimethyl-amine; hydrochloride
• 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride

Amitriptyline hydrochloride

CAS: 549-18-8

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 313.87

Ref: 10-F463103

Amitriptyline Hydrochloride

Controlled Product

CAS: 549-18-8

Applications Amitriptyline HCl is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Tobe, A., et al.: Arzneim.-Forsch., 31, 1278 (1981)2. Jang, S. W., et al.: Chem Biol. 16, 644 (2009)3. Fattahian, E. et al.: IJPR 15, 125 (2016)

Formula: C₂₀H₂₃N·ClH

Color and Shape: Off White

Molecular weight: 313.86

Ref: TR-A633350

Amitryptylline HCl

Controlled Product

CAS: 549-18-8

Tricyclic antidepressant; inhibits norepinephrine and serotonin transporters

Formula: C₂₀H₂₃N·HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 313.86 g/mol

Ref: 3D-FA64940

Amitryptylline hydrochloride - Bio-X ™

Controlled Product

CAS: 549-18-8

Amitryptylline is a tricyclic antidepressant that is used to treat depression and to relieve depression associated anxiety. Although its mechanism is not fully understood, it is suggested that this drug inhibits norepinephrine and serotonin thus increasing their concentrations at the synaptic clefts. Additionally, Amitryptylline has shown to have anticholinergic properties.

Formula: C₂₀H₂₃N•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 313.86 g/mol

Ref: 3D-BA164159