CAS 54965-21-8: Albendazole

Description: Albendazole is a broad-spectrum anthelmintic medication primarily used to treat parasitic infections caused by various worms, including roundworms and tapeworms. It belongs to the benzimidazole class of compounds and functions by inhibiting the polymerization of tubulin, which disrupts the microtubule formation necessary for cellular processes in parasites. This action ultimately leads to the death of the parasites. Albendazole is typically administered orally and is known for its relatively low toxicity in humans. Its solubility is limited in water but is more soluble in organic solvents, which can affect its bioavailability. The compound is often used in veterinary medicine as well as in human medicine, particularly in areas where parasitic infections are prevalent. Side effects may include gastrointestinal disturbances, headache, and, in rare cases, more severe reactions. Due to its mechanism of action and efficacy, albendazole is a critical drug in the management of various helminthic infections.

Formula: C₁₂H₁₅N₃O₂S

InChI: InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key: InChIKey=HXHWSAZORRCQMX-UHFFFAOYSA-N

SMILES: O=C(OC)NC1=NC=2C=C(SCCC)C=CC2N1

Synonyms:

• (5-Propylsulfanyl-1,3-dihydro-benzoimidazol-2-ylidene)-carbamic acid methyl ester
• (5-Propylsulfanyl-1H-Benzoimidazol-2-Yl)-Carbamic Acid Methyl Ester
• (6-Propylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester
• Akos Ncg1-0064
• Albamelin
• Albazine
• Alben
• Albendazol
• Albendazole suspension
• Albendol
• Albenza
• Albenzil
• Aldifal
• Alminth
• Alvet
• Alzental
• Andazol
• Ashialben
• Atasol
• Baxen
• Bruzol
• Carbamic acid, N-[6-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester
• Carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester
• Eskazole
• Exiptol
• Haojing
• Helminsols
• Loveral
• Lurdex
• Methyl 5-propylthio-2-benzimidazolecarbamate
• Nsc 220008
• Skf 62979
• Tobend
• Valbazen
• Vermisen
• Vermitan
• Vermizole
• Vetalben
• Zentel
• [5-(Propylthio)-1H-Benzimidazol-2-Yl]Carbamic Acid, Methyl Ester
• [5-(Propylthio)Benzimidazol-2-Yl]Carbamic Acid Methyl Ester
• methyl [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate
• Albendazole

Albendazole

CAS: 54965-21-8

Anthelmintic; inhibitor of tubulin polymerization

• Formula: C₁₂H₁₅N₃O₂S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 265.33 g/mol