CAS 54965-24-1
:Tamoxifen citrate
Description:
Tamoxifen citrate is a non-steroidal selective estrogen receptor modulator (SERM) primarily used in the treatment of estrogen receptor-positive breast cancer. It functions by binding to estrogen receptors, thereby inhibiting the effects of estrogen on breast tissue, which can promote the growth of certain types of breast tumors. The compound is typically administered orally and is known for its ability to reduce the risk of breast cancer recurrence. Tamoxifen citrate is characterized by its chemical formula, which includes a phenolic structure, and it exhibits both estrogenic and anti-estrogenic properties depending on the target tissue. Its pharmacokinetics involve extensive hepatic metabolism, leading to active metabolites that contribute to its therapeutic effects. Common side effects may include hot flashes, nausea, and an increased risk of thromboembolic events. Due to its significant role in oncology, tamoxifen citrate remains a cornerstone in breast cancer treatment protocols and is also investigated for potential use in other conditions influenced by estrogen.
Formula:C26H29NO·C6H8O7
InChI:InChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;
InChI key:InChIKey=FQZYTYWMLGAPFJ-OQKDUQJOSA-N
SMILES:C(=C(/CC)\C1=CC=CC=C1)(\C2=CC=C(OCCN(C)C)C=C2)/C3=CC=CC=C3.C(CC(O)=O)(CC(O)=O)(C(O)=O)O
Synonyms:- (Z)-2-[4-(1,2-Diphenyl-1-Butenyl)Phenoxyl]-N,N-Dimethyl-Ethanamine-Citrate
- 1-P-Beta-Dimethylaminoethoxyphenyl-Trans-1,2-Diphenylbut-1-Ene Citrate
- 2-{4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt)
- Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- Genox
- I.C.I.46474 citrate
- Ici 46474
- Istubal
- Kessar
- Noltam
- Nolvadex
- Nourytam
- Soltamox
- Tamofen
- Tamoplex
- Tamox-Puren
- Tamoxiphen Citrate
- Tomaxasta
- Valodex
- Z-Tamoxifen citrate
- Zemide
- See more synonyms
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Found 17 products.
Tamoxifen Citrate
CAS:Formula:C26H29NO·C6H8O7Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:563.65Tamoxifen citrate
CAS:<p>Inhibitor of protein kinase C and induces apoptosis in cancer cells</p>Formula:C26H29NO·C6H8O7Molecular weight:563.65TAMOXIFEN CITRATE RS
CAS:<p>TAMOXIFEN CITRATE RS</p>Formula:C32H37NO8Color and Shape:PowderMolecular weight:563.6381TAMOXIFEN CITRATE FOR PERFORMANCE TEST CRS
CAS:<p>TAMOXIFEN CITRATE FOR PERFORMANCE TEST CRS</p>Formula:C32H37NO8Color and Shape:PowderMolecular weight:563.6381Tamoxifen citrate
CAS:Tamoxifen citrateFormula:C26H29NOPurity:65.8%Color and Shape:WhiteMolecular weight:371.22491Tamoxifen Citrate
CAS:<p>Aromatic drugs of amino-alcohols, other than those contg > one kind of oxygen function, their ethers and esters; salts thereof, nesoi</p>Formula:C26H29NO·C6H8O7Color and Shape:White Off-White Crystalline PowderMolecular weight:563.25192Tamoxifen Citrate
CAS:<p>Tamoxifen Citrate is an orally active selective estrogen receptor modulator (SERM) that blocks estrogen activity in breast cells while activating estrogen signaling in cells such as those of the bone, liver, and uterus. As an Hsp90 activator, it enhances the ATPase activity of the Hsp90 chaperone complex, induces autophagy and apoptosis, and can be used to generate gene knockout models in CreER(T2) transgenic mice as well as liver injury models.</p>Formula:C32H37NO8Purity:99.19%Color and Shape:White To Off-White White To Off-White PowderMolecular weight:563.65Tamoxifen citrate
CAS:<p>Tamoxifen citrate</p>Purity:99%Color and Shape:Off-White SolidMolecular weight:563.64g/molTamoxifen Citrate
CAS:Formula:C26H29NO·C6H8O7Color and Shape:White To Off-White SolidMolecular weight:371.53 192.13Tamoxifen citrate salt
CAS:Formula:C26H29NO·C6H8O7Purity:≥ 98.0%Color and Shape:White to almost white powderMolecular weight:563.65Tamoxifen Citrate
CAS:Controlled ProductFormula:C26H29NO·C6H8O7Color and Shape:NeatMolecular weight:563.64Tamoxifen citrate
CAS:Controlled ProductFormula:C26H29NO·C6H8O7Color and Shape:NeatMolecular weight:563.64Tamoxifen Citrate
CAS:Controlled Product<p>Applications Tamoxifen Citrate is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4.<br>References Sutherland, R., et al.: Nature, 267, 434 (1977), Lerner, L., et al.: Cancer Res., 50, 4177 (1990), Love, R., et al.: J. Clin. Oncol., 20 2559 (2002),<br></p>Formula:C26H29NO·C6H8O7Color and Shape:WhiteMolecular weight:563.64Tamoxifen citrate
CAS:Controlled Product<p>Estrogen receptor modulator; protein kinase C inhibitor</p>Formula:C26H29NO·C6H8O7Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:563.64 g/molTamoxifen citrate
CAS:<p>Please enquire for more information about Tamoxifen citrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C32H37NO8Purity:Min. 98.0 Area-%Molecular weight:563.64 g/mol
