CAS 55-03-8
:Levothyroxine sodium
Description:
Levothyroxine sodium, with the CAS number 55-03-8, is a synthetic form of the thyroid hormone thyroxine (T4) used primarily in the treatment of hypothyroidism. It is a white to off-white crystalline powder that is soluble in water and has a molecular formula of C15H11I4NNaO4. The substance acts by increasing the metabolic rate of tissues, influencing protein synthesis, and regulating the metabolism of carbohydrates and fats. Levothyroxine sodium is typically administered orally and is characterized by its high bioavailability and long half-life, allowing for once-daily dosing in most cases. It is essential for maintaining normal growth and development, particularly in children, and plays a critical role in energy metabolism. The drug's potency can be affected by various factors, including the presence of food, other medications, and individual patient characteristics. As with any medication, monitoring of thyroid hormone levels is crucial to ensure therapeutic effectiveness and to avoid potential side effects associated with over- or under-treatment.
Formula:C15H11I4NO4·Na
InChI:InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/t12-;/m0./s1
InChI key:InChIKey=BRLSOHUOWVCKNI-YDALLXLXSA-N
SMILES:O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@@H](C(O)=O)N)C=C2I.[Na]
Synonyms:- <span class="text-smallcaps">L</span>-Thyroxin Henning
- <span class="text-smallcaps">L</span>-Thyroxine monosodium salt
- <span class="text-smallcaps">L</span>-Thyroxine sodium
- <span class="text-smallcaps">L</span>-Thyroxine sodium salt
- <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
- <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
- Berlthyrox
- Dathroid
- Droxine
- Eferox
- Elthyrone
- Elthyroxine
- Eltroxin
- Euthyrox
- Eutirox
- L-Thyroxine sodium
- L-Thyroxine sodium salt
- Laevoxin
- Letrox
- Letter
- Levaxin
- Leventa
- Levo-T
- Levolet
- Levoroxine
- Levothroid
- Levothyrox
- Levotirox
- Levotiroxina
- Levoxyl
- Monosodium thyroxine
- NSC 259940
- Novothyrox
- Oroxine
- Puran T 4
- Sodium 2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl]Propanoate
- Sodium 4-O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine
- Sodium <span class="text-smallcaps">L</span>-thyroxine
- Sodium levothyroxine
- Sodium thyroxin
- Sodium thyroxinate
- Sodium thyroxine
- Synthroid
- Synthroid sodium
- Synthrox
- T 4Kp
- T4 Montpellier 100
- Thevier
- Throxinique
- Thyradin
- Thyradin S
- Thyrax Duotab
- Thyrex
- Thyro 4
- Thyrosit
- Thyroxevan
- Thyroxine sodium
- Thyroxine sodium salt
- Thyroxine, monosodium salt, <span class="text-smallcaps">L</span>-
- Tiroidine
- Tirosint
- Unithroid
- tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
- L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
- L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
L-Thyroxine Sodium Salt Pentahydrate
CAS:Formula:C15H10I4NNaO4·5H2OPurity:>98.0%(T)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:888.94Levothyroxine sodium impurity standard
CAS:Levothyroxine sodium impurity standardColor and Shape:White To Off-WhiteLiothyronine sodium impurity standard
CAS:Liothyronine sodium impurity standardColor and Shape:White To Off-WhiteL-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodiumsalt
CAS:Formula:C15H10I4NNaO4Purity:99%Color and Shape:SolidMolecular weight:798.8518L-Thyroxine sodium
CAS:<p>L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.</p>Formula:C15H10I4NO4·NaPurity:98.74%Color and Shape:Yellowish To Buff-Colored Amorphous Powder SolidMolecular weight:798.85Thyroxine Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.<br>References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),<br></p>Formula:C15H10I4NO4·NaColor and Shape:NeatMolecular weight:798.85Levothyroxine sodium
CAS:<p>Levothyroxine sodium is a thyroid hormone that is used to treat hypothyroidism. It is also used to treat goiter and other thyroid problems. Levothyroxine sodium comes in three different forms: tablets, oral solution, and levothyroxine sodium for injection. The tablet form of levothyroxine sodium is taken by mouth once daily with or without food. Oral solution is taken by mouth twice daily (morning and evening) with or without food. Injection should be given as directed by a physician or healthcare provider. Levothyroxine sodium can interact with many drugs, especially ones that affect the heart or blood sugar levels, such as potassium supplements, diuretics, beta blockers, calcium channel blockers, erythromycin, clarithromycin and ketoconazole. Levothyroxine sodium can also interact with certain foods such as soybean flour and grapefruit juice. Levothyroxine sodium has been shown to have a linear calibration curve in vivo</p>Formula:C15H10I4NNaO4Purity:Min. 95%Color and Shape:White PowderMolecular weight:798.85 g/mol
