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CAS 55-03-8

:

Levothyroxine sodium

Description:
Levothyroxine sodium, with the CAS number 55-03-8, is a synthetic form of the thyroid hormone thyroxine (T4) used primarily in the treatment of hypothyroidism. It is a white to off-white crystalline powder that is soluble in water and has a molecular formula of C15H11I4NNaO4. The substance acts by increasing the metabolic rate of tissues, influencing protein synthesis, and regulating the metabolism of carbohydrates and fats. Levothyroxine sodium is typically administered orally and is characterized by its high bioavailability and long half-life, allowing for once-daily dosing in most cases. It is essential for maintaining normal growth and development, particularly in children, and plays a critical role in energy metabolism. The drug's potency can be affected by various factors, including the presence of food, other medications, and individual patient characteristics. As with any medication, monitoring of thyroid hormone levels is crucial to ensure therapeutic effectiveness and to avoid potential side effects associated with over- or under-treatment.
Formula:C15H11I4NO4·Na
InChI:InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/t12-;/m0./s1
InChI key:InChIKey=BRLSOHUOWVCKNI-YDALLXLXSA-N
SMILES:O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@@H](C(O)=O)N)C=C2I.[Na]
Synonyms:
  • <span class="text-smallcaps">L</span>-Thyroxin Henning
  • <span class="text-smallcaps">L</span>-Thyroxine monosodium salt
  • <span class="text-smallcaps">L</span>-Thyroxine sodium
  • <span class="text-smallcaps">L</span>-Thyroxine sodium salt
  • <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
  • <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
  • Berlthyrox
  • Dathroid
  • Droxine
  • Eferox
  • See more synonyms
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