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CAS 55-43-6

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Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochloride (1:1)

Description:
Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochloride (1:1), commonly known as chlorpromazine, is an antipsychotic medication primarily used to treat schizophrenia and other mental health disorders. It belongs to the class of phenothiazines and exhibits a range of pharmacological effects, including sedative, antiemetic, and anticholinergic properties. The compound features a phenothiazine core structure, which contributes to its ability to block dopamine receptors in the brain, thereby alleviating symptoms of psychosis. Chlorpromazine is typically administered in its hydrochloride salt form, enhancing its solubility and stability. The substance is characterized by its moderate lipophilicity, allowing it to cross the blood-brain barrier effectively. It may also interact with various neurotransmitter systems, including serotonin and adrenergic receptors, leading to a diverse profile of therapeutic effects and potential side effects. Due to its pharmacological activity, chlorpromazine requires careful dosing and monitoring to manage its efficacy and minimize adverse reactions.
Formula:C16H18ClN·ClH
InChI:InChI=1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H
InChI key:InChIKey=LZXCEBPGNFLHEQ-UHFFFAOYSA-N
SMILES:N(CC1=CC=CC=C1)(CC2=CC=CC=C2)CCCl.Cl
Synonyms:
  • (2-Chloroethyl)dibenzylamine hydrochloride
  • (N,N-Dibenzylamino)ethyl chloride hydrochloride
  • (β-Chloroethyl)dibenzylamine hydrochloride
  • 2-(Dibenzylamino)ethyl chloride hydrochloride
  • Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochloride
  • Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochloride (1:1)
  • Dibenamine hydrochloride
  • Dibenzylamine, N-(2-chloroethyl)-, hydrochloride
  • N,N-Dibenzyl-2-chloroethanamine hydrochloride
  • N,N-Dibenzyl-β-chloroethylamine hydrochloride
  • See more synonyms
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