CAS 55-86-7: Nitrogen mustard

Description: Nitrogen mustard refers to a class of chemical compounds derived from mustard gas, specifically characterized by the presence of nitrogen atoms in their structure. The compound with CAS number 55-86-7 is known as mechlorethamine, a type of nitrogen mustard that has been utilized primarily in chemotherapy for treating certain types of cancer, such as Hodgkin's lymphoma and non-Hodgkin's lymphoma. Mechlorethamine is a potent alkylating agent, meaning it can form covalent bonds with DNA, leading to cross-linking and ultimately inhibiting DNA replication and transcription, which is crucial for cancer cell proliferation. This compound is typically administered intravenously due to its instability in solution and potential for severe local tissue damage if extravasation occurs. In addition to its therapeutic uses, nitrogen mustards can exhibit toxic effects, including nausea, vomiting, and myelosuppression, which necessitates careful monitoring during treatment. Overall, nitrogen mustards represent a significant advancement in cancer therapy, although their use is accompanied by notable side effects and risks.

Formula: C₅H₁₁Cl₂N·ClH

InChI: InChI=1S/C5H11Cl2N.ClH/c1-8(4-2-6)5-3-7;/h2-5H2,1H3;1H

InChI key: InChIKey=QZIQJVCYUQZDIR-UHFFFAOYSA-N

SMILES: Cl.ClCCN(C)CCCl

Synonyms:

• 1,5-Dichloro-3-methyl-3-azapentane hydrochloride
• 2,2'-Dichloro-N-methyldiethylamine hydrochloride
• 2-Chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride
• 2-chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride (1:1)
• Antimit
• Azotoyperite
• Bis(2-chloroethyl)-N-methylamine hydrochloride
• Bis(2-chloroethyl)methylamine hydrochloride
• C 6866
• Caryolysine
• Caryolysine hydrochloride
• Chloramin
• Chloramin hydrochloride
• Chloramine
• Chlorethamine
• Chlormethine Hydrochloride
• Chlormethine, Chlorhydrate
• Chlormethinhydrochlorid
• Chlormethinum
• Chloromethine Hydrochloride
• Clorometina, Clorhidrato
• Dema
• Dichloren
• Dichloren hydrochloride
• Dichloromethyldiethylamine hydrochloride
• Diethylamine, 2,2'-dichloro-N-methyl-, hydrochloride
• Dimitan
• Embechine
• Embichin
• Embichin hydrochloride
• Embikhine
• Embiquine
• Erasol
• Erasol hydrochloride
• Erasol-Ido
• Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-, hydrochloride
• Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-, hydrochloride (1:1)
• HN2 hydrochloride
• HN₂ hydrochloride
• Kloramin
• MBA hydrochloride
• Mechlorothamine
• Methylbis(2-chloroethyl)amine hydrochloride
• Methylbis(β-chloroethyl)amine hydrochloride
• Mitoxine
• Mustargen hydrochloride
• Mustine hydrochloride
• N,N-Bis(2-chloroethyl)methanamine hydrochloride
• N-Lost
• N-Methyl-N,N-bis(2-chloroethyl)amine hydrochloride
• N-Methylbis(2-chloroethyl)amine hydrochloride
• N-methyl-bis(2-chloroethyl)amine hydrochloride
• NM
• NSC 762 hydrochloride
• Nci C56382
• Nitol
• Nitol takeda
• Nitrogen Mustard Hydrochloride
• Nitrogen mustard
• Nitrogen mustard (HN 2) hydrochloride
• Nitrogranulogen
• Nitrogranulogen hydrochloride
• Nsc 762
• Sk 101

Bis(2-chloroethyl)-N-methylamine hydrochloride

CAS: 55-86-7

• Formula: C₅H₁₂Cl₃N
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 192.5145

Chlormethine hydrochloride

CAS: 55-86-7

• Formula: C₅H₁₁Cl₂N·HCl
• Purity: ≥ 97.5%
• Color and Shape: White to almost white powder or crystals
• Molecular weight: 192.52

Mechlorethamine Hydrochloride

CAS: 55-86-7

• Formula: C₅H₁₁Cl₂N·ClH
• Color and Shape: Neat
• Molecular weight: 192.51

Bis(2-chloroethyl)methylamine Hydrochloride

CAS: 55-86-7

• Formula: C₅H₁₁Cl₂N·ClH
• Color and Shape: Neat
• Molecular weight: 192.51

Mechlorethamine Hydrochloride

CAS: 55-86-7

Acyclic monoamines and their derivatives, nesoi

• Formula: C₅H₁₁Cl₂N·HCl
• Color and Shape: White Powder
• Molecular weight: 155.02685