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CAS 55-86-7

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Nitrogen mustard

Description:
Nitrogen mustard refers to a class of chemical compounds derived from mustard gas, specifically characterized by the presence of nitrogen atoms in their structure. The compound with CAS number 55-86-7 is known as mechlorethamine, a type of nitrogen mustard that has been utilized primarily in chemotherapy for treating certain types of cancer, such as Hodgkin's lymphoma and non-Hodgkin's lymphoma. Mechlorethamine is a potent alkylating agent, meaning it can form covalent bonds with DNA, leading to cross-linking and ultimately inhibiting DNA replication and transcription, which is crucial for cancer cell proliferation. This compound is typically administered intravenously due to its instability in solution and potential for severe local tissue damage if extravasation occurs. In addition to its therapeutic uses, nitrogen mustards can exhibit toxic effects, including nausea, vomiting, and myelosuppression, which necessitates careful monitoring during treatment. Overall, nitrogen mustards represent a significant advancement in cancer therapy, although their use is accompanied by notable side effects and risks.
Formula:C5H12Cl3N
InChI:InChI=1/C5H11Cl2N.ClH/c6-3-1-5(8)2-4-7;/h5H,1-4,8H2;1H
InChI key:InChIKey=QZIQJVCYUQZDIR-UHFFFAOYSA-N
SMILES:N(CCCl)(CCCl)C.Cl
Synonyms:
  • 1,5-Dichloro-3-methyl-3-azapentane hydrochloride
  • 2,2'-Dichloro-N-methyldiethylamine hydrochloride
  • 2-Chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride
  • 2-chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride (1:1)
  • Antimit
  • Azotoyperite
  • Bis(2-chloroethyl)-N-methylamine hydrochloride
  • Bis(2-chloroethyl)methylamine hydrochloride
  • C 6866
  • Caryolysine
  • See more synonyms
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