CAS 55-97-0: Hexamethonium bromide

Description: Hexamethonium bromide is a quaternary ammonium compound characterized by its use as a ganglionic blocker in pharmacology. It is a white to off-white crystalline powder that is soluble in water and exhibits a strong ionic nature due to the presence of the bromide ion. The compound acts primarily by inhibiting the transmission of nerve impulses in the autonomic nervous system, particularly at the ganglia, which makes it useful in the treatment of hypertension and other conditions related to autonomic dysfunction. Hexamethonium bromide has a relatively low toxicity profile but can cause side effects such as hypotension, dry mouth, and constipation due to its systemic effects on the autonomic nervous system. Its mechanism of action involves competitive antagonism at nicotinic acetylcholine receptors, leading to a decrease in sympathetic and parasympathetic activity. While it has historical significance in clinical settings, its use has declined with the advent of more selective and safer antihypertensive agents.

Formula: C₁₂H₃₀N₂·2Br

InChI: InChI=1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

InChI key: InChIKey=FAPSXSAPXXJTOU-UHFFFAOYSA-L

SMILES: [Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C

Synonyms:

• 1,6-Bis(trimethylammonium)hexane dibromide
• 1,6-Hexanebis(trimethylammonium) dibromide
• 1,6-Hexanediaminium, N,N,N,N′,N′,N′-hexamethyl-, dibromide
• 1,6-Hexanediaminium, N¹,N¹,N¹,N⁶,N⁶,N⁶-hexamethyl-, bromide (1:2)
• Ammonium, hexamethylenebis[trimethyl-, dibromide
• Bistrium bromide
• Esametina
• Gangliostat
• Hexamethone bromide
• Hexamethonium bromide hydrate
• Hexamethonium dibromide
• Hexamethylenebis(trimethylammonium bromide) hydrate
• Hexamethylenebis(trimethylammonium) dibromide
• Hexamethylenebis[trimethylammonium bromide]
• Hexameton
• Hexameton bromide
• Hexane-1,6-bis(trimethylammonium bromide)
• Hexanium bromide
• Hexonium dibromide
• Methobromin
• Methobromine
• N,N,N,N',N',N'-Hexamethylhexane-1,6-diammonium dibromide
• N,N,N,N',N',N'-hexamethylhexane-1,6-diaminium dibromide
• N,N,N,N′,N′,N′-Hexamethyl(hexamethylene)diammonium bromide
• Simpatoblock
• Vegolysen
• Vegolysin
• C 6
• 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, bromide (1:2)

Hexamethonium Bromide

CAS: 55-97-0

• Formula: C₁₂H₃₀Br₂N₂
• Purity: >98.0%(T)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 362.19

Hexamethonium bromide, 98+%

CAS: 55-97-0

Nicotinic acetyl choline receptor antagonist This Thermo Scientific Chemicals brand product was originally part of …

• Formula: C₁₂H₃₀Br₂N₂
• Purity: 98+%
• Molecular weight: 362.19

Hexamethonium Bromide

CAS: 55-97-0

Hexamethonium Bromide blocks neural nicotinic AChR, poorly absorbed in the gut, doesn't pass the blood-brain …

• Formula: C₁₂H₃₀Br₂N₂
• Purity: 99.76%
• Color and Shape: White Crystalline Powder And Agglomerates
• Molecular weight: 362.19

HEXAMETHONIUM BROMIDE

CAS: 55-97-0

• Formula: C₁₂H₃₀Br₂N₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 362.188

N1,N1,N1,N6,N6,N6-Hexamethylhexane-1,6-Diaminium Bromide

CAS: 55-97-0

• Purity: 98%+
• Molecular weight: 362.19g/mol

Hexamethonium Bromide

CAS: 55-97-0

• Purity: 99.87%
• Molecular weight: 362.19g/mol

HEXAMETHONIUM BROMIDE

CAS: 55-97-0

• Purity: 95%
• Molecular weight: 362.1940002441406

Hexamethonium Bromide

CAS: 55-97-0

Applications Hexamethonium bromide is a nicotinic ACh receptor antagonist.

• Formula: C₁₂H₃₀Br₂N₂
• Color and Shape: Neat
• Molecular weight: 362.19

Hexamethonium bromide

CAS: 55-97-0

Hexamethonium bromide is a nicotinic receptor antagonist that blocks the action of acetylcholine at the …

• Formula: C₁₂H₃₀Br₂N₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 362.19 g/mol