CAS 550-33-4
:Nebularine
Description:
Nebularine, with the CAS number 550-33-4, is a naturally occurring nucleoside derived from the purine base adenine. It is characterized by its structural composition, which includes a ribose sugar linked to the adenine base. Nebularine is notable for its role in various biological processes and has been studied for its potential therapeutic applications, particularly in the field of antiviral and anticancer research. The compound exhibits solubility in water, which facilitates its biological activity. Its molecular structure allows for interactions with nucleic acids, influencing cellular mechanisms. Additionally, nebularine has been investigated for its effects on enzyme activity and its potential to modulate immune responses. While it is not widely used in clinical settings, ongoing research continues to explore its pharmacological properties and possible applications in medicine. As with many nucleosides, its stability and reactivity can be influenced by environmental factors such as pH and temperature, making it an interesting subject for further study in biochemistry and pharmacology.
Formula:C10H12N4O4
InChI:InChI=1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s1
InChI key:InChIKey=MRWXACSTFXYYMV-FDDDBJFASA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=CN=CN3)O[C@H](CO)[C@H]1O
Synonyms:- 9-(alpha-D-xylofuranosyl)-9H-purinato(2-)
- 9-(beta-D-ribofuranosyl)-9H-purine
- 9-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-9H-purine
- 9-β-<span class="text-smallcaps">D</span>-Ribofuranosylpurine
- 9-β-<span class="text-smallcaps">D</span>-Ribosyl-9H-purine
- 9H-Purine, 9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- Desaminoadenosine
- Isopurine, ribosyl-
- NSC 65423
- Nebularine
- Purine Riboside
- Purine-9-β-<span class="text-smallcaps">D</span>-ribofuranoside
- Purinosine
- Ribosylpurine
- 9-β-D-Ribofuranosyl-9H-purine
- See more synonyms
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Found 8 products.
Nebularine
CAS:Formula:C10H12N4O4Purity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:252.23Nebularine
CAS:Nebularine, a purine nucleoside analog, inhibits DNA synthesis, induces apoptosis, and has broad antitumor effects, especially against lymphoid cancers.Formula:C10H12N4O4Purity:99.59%Color and Shape:SolidMolecular weight:252.239-(b-D-Ribofuranosyl)purine
CAS:Formula:C10H12N4O4Purity:(HPLC) ≥ 98.0%Color and Shape:White to off-white solidMolecular weight:252.29-(b-D-Ribofuranosyl)purine
CAS:9-(b-D-Ribofuranosyl)purine (9-BRP) is a purine nucleoside that is used in the synthesis of dyes. It has been shown to be an effective inhibitor of the enzyme phosphodiesterase 3B, which breaks down cyclic adenosine monophosphate (cAMP), and therefore can prevent kidney fibrosis. 9-BRP has also been shown to inhibit the synthesis of collagen by binding to cAMP. In addition, 9-BRP binds to DNA and forms hydrogen bonds with nitrogen atoms on the phosphate groups in DNA. This interaction prevents the formation of hydrogen bonds between water molecules in water vapor and phosphate groups, thus slowing down their rate of dissociation from each other. 9-BRP also has a high affinity for Toll-like receptor 4 (TLR4), which is involved in the inflammatory response, making it an ideal therapeutic candidate for treating inflammation and renal fibrosis.Formula:C10H12N4O4Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:252.23 g/molNebularine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria.<br>References Iwamura, H. and Hashizume, T.: J.O.C., 33, 5 1796 (1968)<br></p>Formula:C10H12N4O4Color and Shape:NeatMolecular weight:252.23
