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CAS 550-54-9

:

(8α,9S)-Cinchonan-9-ol

Description:
(8α,9S)-Cinchonan-9-ol, with the CAS number 550-54-9, is a naturally occurring alkaloid derived from the cinchona tree, known for its role in traditional medicine, particularly in the treatment of malaria. This compound features a bicyclic structure characteristic of the cinchona alkaloids, which includes a quinoline moiety. It is a chiral molecule, possessing specific stereochemistry that contributes to its biological activity. The hydroxyl group at the 9-position is crucial for its pharmacological properties, influencing interactions with biological targets. (8α,9S)-Cinchonan-9-ol exhibits moderate solubility in organic solvents and is typically less soluble in water, reflecting its hydrophobic characteristics. Its potential applications extend beyond medicinal uses, including roles in asymmetric synthesis and as a chiral auxiliary in organic chemistry. The compound's unique structural features and stereochemistry make it a subject of interest in both pharmaceutical research and synthetic organic chemistry.
Formula:C19H22N2O
InChI:InChI=1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18-,19-/m0/s1
InChI key:InChIKey=KMPWYEUPVWOPIM-LSOMNZGLSA-N
SMILES:[C@@H](O)([C@]1([N@@]2C[C@H](C=C)[C@](C1)(CC2)[H])[H])C=3C4=C(N=CC3)C=CC=C4
Synonyms:
  • Cinchonan-9-ol, (8α,9S)-
  • (8α,9S)-Cinchonan-9-ol
  • (+)-9-epi-Cinchonidine
  • 9-epi-Cinchonidine
  • Epicinchonidine
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Found 1 products.
  • 9-Epi-cinchonidine
    Biosynth
    + Info

    9-Epi-cinchonidine

    CAS:
    <p>9-Epi-cinchonidine is an analog of the natural product cinchonidine and has been found to have potent anticancer activity. It acts as a kinase inhibitor, specifically targeting cyclin-dependent kinases (CDKs), which are involved in cell cycle regulation. 9-Epi-cinchonidine has been shown to induce apoptosis in cancer cells, including those from Chinese hamster ovary and human urinary bladder carcinoma. This compound also inhibits the growth of cancer cells by blocking protein synthesis and promoting cell death. Additionally, 9-Epi-cinchonidine has been found to have potential as an inhibitor for Dabigatran, a drug used to prevent blood clots. Overall, this compound holds promise as a potential therapeutic agent for cancer treatment.</p>
    Formula:C19H22N2O
    Purity:Min. 95%
    Molecular weight:294.4 g/mol

    Ref: 3D-AAA55054

    1g
    1,019.00€