CAS 550-70-9

Triprolidine hydrochloride

Description:

Triprolidine hydrochloride is an antihistamine primarily used to alleviate symptoms associated with allergic reactions, such as hay fever and other respiratory allergies. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, often leading to sedative effects. The chemical structure of triprolidine includes a piperidine ring, contributing to its pharmacological properties. As a hydrochloride salt, it is typically presented in a crystalline form, enhancing its solubility in water. The substance exhibits a relatively low toxicity profile when used as directed, but it may cause side effects such as drowsiness, dry mouth, and dizziness. Triprolidine acts by blocking H1 histamine receptors, thereby reducing the physiological effects of histamine, which include vasodilation and increased vascular permeability. It is important to use this medication under medical supervision, especially in populations such as the elderly or those with pre-existing health conditions, due to potential interactions with other medications and the risk of exacerbating certain health issues.

Formula: C₁₉H₂₂N₂·ClH

InChI: InChI=1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+;

InChI key: InChIKey=WYUYEJNGHIOFOC-NWBUNABESA-N

SMILES: C(=C\CN1CCCC1)(\C2=CC=C(C)C=C2)/C3=CC=CC=N3.Cl

Synonyms:

• (E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride
• 2-(1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)pyridine monohydrochloride
• 295C51
• Actidil
• Actidilat
• Actidilon
• Entra
• Pro-Actidil
• Pro-Entra
• Pyridine, 2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-, hydrochloride (1:1)
• Pyridine, 2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride
• Pyridine, 2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride, (E)-
• Pyridine, 2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-, monohydrochloride, (E)-
• Triprolidine hcl
• Venen
• trans-1-(4-Methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene hydrochloride
• trans-2-[3-(1-Pyrrolidinyl)-1-(p-tolyl)propenyl]pyridine hydrochloride

(E)-2-(3-(Pyrrolidin-1-yl)-1-(p-tolyl)prop-1-en-1-yl)pyridine hydrochloride

CAS: 550-70-9

Formula: C₁₉H₂₃ClN₂

Color and Shape: Solid

Molecular weight: 314.8523

Ref: IN-DA00DEIN

Triprolidine-d8 HCl

CAS: 550-70-9

Formula: C₁₉H₁₄D₈N₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 286.45 36.46

Ref: 4Z-T-773

Triprolidine HCl

CAS: 550-70-9

Formula: C₁₉H₂₂N₂·HCl

Molecular weight: 278.40 36.46

Ref: 4Z-T-774

Triprolidine hydrochloride

CAS: 550-70-9

Triprolidine hydrochloride anhydrous, a Histamine H1 antagonist, is used in asthma, allergic rhinitis, and urticaria.

Formula: C₁₉H₂₃ClN₂

Color and Shape: Solid

Molecular weight: 314.852

Ref: TM-T21112

Triprolidine Hydrochloride

Controlled Product

CAS: 550-70-9

Applications Triprolidine is an antihistaminic agent with anticholinergic properties. Triprolidine is used to treat and prevent symptoms associated with allergies. Triprolidine is also used in combination with cold medicine to provide relief for flu-like symptoms.
References Bye, C. et al.: Br. J. Clin. Pharmacol., 1, 342 (1974); Fantozzi, R. et al.: Br. J. Pharmacol., 53, 569 (1975);

Formula: C₁₉H₂₂N₂·ClH

Color and Shape: Neat

Molecular weight: 314.85

Ref: TR-T814000

Triprolidine Hydrochloride

CAS: 550-70-9

Formula: C₁₉H₂₂N₂HCl

Molecular weight: 278.40 : 36.46

Ref: ST-EA-CP-T190003