CAS 5502-78-3

9-Methylguanine

Description:

9-Methylguanine is a derivative of guanine, one of the four primary nucleobases in the nucleic acids DNA and RNA. It is characterized by the presence of a methyl group attached to the nitrogen atom at the 9-position of the purine ring. This modification can influence the molecule's biological activity and stability, as methylation is a common epigenetic modification that can affect gene expression. 9-Methylguanine is known to participate in various biochemical processes, including DNA repair and replication, and can also play a role in mutagenesis. Its structure allows it to pair with cytosine during DNA synthesis, which can lead to transitions in the genetic code. The compound is of interest in research related to cancer, as aberrant methylation patterns are often associated with tumorigenesis. Additionally, 9-Methylguanine can be used as a model compound in studies of nucleobase modifications and their effects on nucleic acid interactions. Its CAS number, 5502-78-3, is a unique identifier that facilitates its identification in chemical databases and literature.

Formula: C₆H₇N₅O

InChI: InChI=1S/C6H7N5O/c1-11-2-8-3-4(11)9-6(7)10-5(3)12/h2H,1H3,(H3,7,9,10,12)

InChI key: InChIKey=UUWJNBOCAPUTBK-UHFFFAOYSA-N

SMILES: O=C1C2=C(NC(N)=N1)N(C)C=N2

Synonyms:

• 2-Amino-1,9-dihydro-9-methyl-6H-purin-6-one
• 2-Amino-9-methyl-1,9-dihydro-purin-6-one
• 2-Amino-9-methyl-1H-purin-6(9H)-one
• 2-Amino-9-methyl-3H-purin-6-one
• 2-Amino-9-methyl-6,9-dihydro-3H-purin-6-one
• 2-Amino-9-methyl-9H-purin-6-ol
• 2-Imino-9-methyl-2,3,6,9-tetrahydro-1H-purin-6-one
• 2-amino-9-methyl-3,9-dihydro-6H-purin-6-one
• 6H-Purin-6-one, 2-amino-1,9-dihydro-9-methyl-
• Guanine, 9-methyl-
• N⁹-Methylguanine
• Nsc 19065
• 9-Methylguanine

9-METHYLGUANINE

CAS: 5502-78-3

Formula: C₆H₇N₅O

Purity: 95%

Color and Shape: Solid

Molecular weight: 165.1527

Ref: IN-DA00DLL7

2-Amino-9-methyl-1H-purin-6(9H)-one

CAS: 5502-78-3

2-Amino-9-methyl-1H-purin-6(9H)-one

Purity: 95%

Molecular weight: 165.16g/mol

Ref: 54-OR1048553

9-Methylguanine

CAS: 5502-78-3

Ref: 7W-GW8077

9-Methylguanine

CAS: 5502-78-3

9-Methylguanine is a tautomer of guanine, which has been shown to be an autoantigen in autoimmune diseases such as bowel disease. 9-Methylguanine's activity index is 2,500 times higher than the other tautomer. The antigenicity of 9-methylguanine and its ability to bind to antibodies suggest that it could serve as a model system for studying the molecular basis of autoimmune diseases. The reaction mechanism of 9-methylguanine has been studied by using chemical biology approaches, which revealed that this molecule forms hydrogen bonds with itself and other molecules in order to stabilize its structure.

Formula: C₆H₇N₅O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 165.15 g/mol

Ref: 3D-FAA50278