CAS 550368-41-7

1H-[1,2,4]Triazolo[1,2-a]pyridazine-5-carboxamide,2-(3-cyanophenyl)-2,3,7,8-tetrahydro-1,3,7-trioxo-N-(phenylmethyl)-

Description:

1H-[1,2,4]Triazolo[1,2-a]pyridazine-5-carboxamide, with the CAS number 550368-41-7, is a complex organic compound characterized by its unique triazole and pyridazine ring structures. This compound features a carboxamide functional group, which contributes to its potential solubility in polar solvents and may influence its biological activity. The presence of a tetrahydro-1,3,7-trioxo moiety suggests that it may exhibit interesting reactivity and stability under various conditions. Additionally, the substitution with a 3-cyanophenyl group and a phenylmethyl group indicates potential for diverse interactions in biological systems, making it a candidate for pharmaceutical applications. The compound's structural complexity may also impart unique electronic properties, which could be relevant in medicinal chemistry. Overall, this substance's characteristics, including its molecular structure and functional groups, suggest potential utility in drug development and other chemical applications, although specific biological activities would require further investigation.

Formula: C₂₁H₁₅N₅O₄

PNRI-299

CAS: 550368-41-7

PNRI-299 is a synthetic small molecule that has been shown to inhibit cancer cell growth by targeting the transcriptional regulator protein, nuclear factor κB (NF-κB). NF-κB is a redox signal that regulates the expression of genes involved in cellular responses to stress. PNRI-299 has been shown to suppress the expression of these genes, leading to decreased proliferation and increased apoptosis. PNRI-299 also inhibits the transition from G1 to S phase in cells; thus it may be used as an anti-cancer drug.

Formula: C₂₁H₁₅N₅O₄

Purity: Min. 95%

Molecular weight: 401.4 g/mol

Ref: 3D-AXA36841

PNRI-299

CAS: 550368-41-7

PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).

Formula: C₂₁H₁₅N₅O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 401.37

Ref: TM-T12508