CAS 5505-63-5

D-Mannosamine hydrochloride

Description:

D-Mannosamine hydrochloride is an amino sugar and a derivative of mannose, characterized by the presence of an amine group (-NH2) at the C-2 position. It appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various biological applications. The hydrochloride form enhances its stability and solubility. D-Mannosamine plays a crucial role in glycoprotein synthesis and is involved in cellular processes, including cell signaling and adhesion. It is often studied for its potential therapeutic applications, particularly in the fields of immunology and cancer research, due to its ability to influence glycosylation patterns on cell surfaces. Additionally, it can serve as a substrate for the synthesis of other biologically relevant compounds. As with many amino sugars, it is important to handle D-mannosamine hydrochloride with care, following appropriate safety protocols, as it may have biological effects that require further investigation in specific contexts.

Formula: C₆H₁₃NO₅·ClH

InChI: InChI=1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4-,5-,6-;/m1./s1

InChI key: InChIKey=CBOJBBMQJBVCMW-MVNLRXSJSA-N

SMILES: [C@H]([C@@H]([C@@H](CO)O)O)([C@@H](C=O)N)O.Cl

Synonyms:

• (3R,4S,5R)-3,4,5,6-tetrahydroxy-L-norleucine hydrochloride (1:1)
• 2-Amino-2-deoxy-<span class="text-smallcaps">D</span>-mannose hydrochloride
• 2-Amino-2-deoxy-D-mannopyranose hydrochloride
• 2-amino-2-deoxy-D-mannose hydrochloride
• <span class="text-smallcaps">D</span>-(+)-Mannosamine hydrochloride
• <span class="text-smallcaps">D</span>-Mannose, 2-amino-2-deoxy-, hydrochloride
• <span class="text-smallcaps">D</span>-Mannose, 2-amino-2-deoxy-, hydrochloride (1:1)
• D-Mannosamine, HCl
• Mannose, 2-amino-2-deoxy-, hydrochloride, <span class="text-smallcaps">D</span>-
• D-Mannosamine hydrochloride
• D-Mannose, 2-amino-2-deoxy-, hydrochloride
• D-Mannosamine, Hydrochloride
• Mannose, 2-amino-2-deoxy-, hydrochloride, D-

D-Mannosamine Hydrochloride

CAS: 5505-63-5, 6730-09-2

Formula: C₆H₁₃NO₅·HCl

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 215.63

Ref: 3B-M3237

D-Mannosamine hydrochloride, 98%

CAS: 5505-63-5

D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propano

Formula: C₆H₁₄ClNO₆

Purity: 98%

Color and Shape: White to off-white, Powder

Molecular weight: 231.63

Ref: 02-J66316

2-Amino-2-deoxy-D-mannose hydrochloride

CAS: 5505-63-5

Formula: C₆H₁₄ClNO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 215.6321

Ref: IN-DA0038N9

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride, 10mM (in DMSO)

CAS: 5505-63-5

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride, 10mM (in DMSO)

Purity: ≥95%

Molecular weight: 215.63g/mol

Ref: 54-BUP19963

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

CAS: 5505-63-5

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

Purity: ≥98%

Molecular weight: 215.63g/mol

Ref: 54-BUP17602

D-Mannosamine hydrochloride

CAS: 5505-63-5

D-Mannosamine hydrochloride

Formula: C₆H₁₃NO₅·ClH

Purity: By hplc: 99.6% (Typical Value in Batch COA)

Color and Shape: white crystalline powder

Molecular weight: 215.63g/mol

Ref: 54-BIM4501

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

CAS: 5505-63-5

Formula: C₆H₁₄ClNO₅

Purity: 95%

Color and Shape: Liquid, No data available.

Molecular weight: 215.63

Ref: 10-F093487

D-Mannosamine hydrochloride

CAS: 5505-63-5

Formula: C₆H₁₃NO₅·HCl

Purity: (TLC) ≥ 98.0%

Color and Shape: White crystalline powder

Molecular weight: 215.63

Ref: 7W-GC1764

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

CAS: 5505-63-5

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride (D-Mannosamine hydrochloride) is a compound used in the development of mannosylated liposomes.

Formula: C₆H₁₄ClNO₅

Purity: 99.13% - 99.67%

Color and Shape: Powder To Fine Crystals White/Colorless

Molecular weight: 215.63

Ref: TM-T4709

D-Mannosamine Hydrochloride

CAS: 5505-63-5

Applications A pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery via M cells of Peyer's patches.
References Pukanud, P. et al.: Drug Delivery, 16, 289 (2009); Knowles, D.J. et al.: J. Gen. Microbiol., 108, 17 (1978);

Formula: C₆H₁₃NO₅·ClH

Color and Shape: Neat

Molecular weight: 215.63

Ref: TR-M167000

D-Mannosamine HCl

CAS: 5505-63-5

Resource for synthesis of non-natural ManNAc analogs and mannosaminyl donors

Formula: C₆H₁₃NO₅·HCl

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 215.63 g/mol

Ref: 3D-MM04214

D-Mannosamine Hydrochloride extrapure, 98%

CAS: 5505-63-5

Formula: C₆H₁₃NO₅HCI

Purity: min. 98%

Color and Shape: White to off white, Crystalline powder, Clear

Molecular weight: 215.64

Ref: SR-94551