CAS 551-15-5

Liquiritin

Description:

Liquiritin is a flavonoid glycoside primarily derived from the root of Glycyrrhiza glabra, commonly known as licorice. It is characterized by its sweet taste, which is attributed to its structural components. The compound exhibits a range of biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties, making it of interest in both traditional medicine and modern pharmacology. Liquiritin is soluble in water and organic solvents, which facilitates its extraction and use in various formulations. Its chemical structure consists of a flavonoid backbone with a glucose moiety, contributing to its solubility and bioactivity. Additionally, liquiritin has been studied for its potential effects on skin health and its role in enhancing the absorption of other therapeutic compounds. As a natural product, it is often considered safe for consumption, although further research is necessary to fully understand its pharmacokinetics and long-term effects. Overall, liquiritin represents a significant compound in the field of natural products and herbal medicine.

Formula: C₂₁H₂₂O₉

InChI: InChI=1S/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-4-1-10(2-5-12)15-8-14(24)13-6-3-11(23)7-16(13)29-15/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1

InChI key: InChIKey=DEMKZLAVQYISIA-ZRWXNEIDSA-N

SMILES: O=C1C=2C(O[C@@H](C1)C3=CC=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3)=CC(O)=CC2

Synonyms:

• (2S)-2-[4-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
• (S)-7-Hydroxy-2-[4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyltetrahydropyran-2-yloxy)phenyl]chroman-4-one
• 4-[(2S)-7-hydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl]phenyl beta-D-glucopyranoside
• 4H-1-Benzopyran-4-one, 2-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (2S)-
• 4H-1-Benzopyran-4-one, 2-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (S)-
• 4′,7-Dihydroxyflavanone 4′-β-<span class="text-smallcaps">D</span>-glucopyranoside
• 4′,7-Dihydroxyflavanone 4′-β-<span class="text-smallcaps">D</span>-glucoside
• 7-Hydroxyflavanone 4′-O-glucoside
• Likviritin
• Liquiritigenin 4′-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Liquiritin(Sh)
• Liquiritoside
• Liquiritin
• (2S)-2-[4-(β-D-Glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 2-[4-(β-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (2S)-

Liquiritin

CAS: 551-15-5

Formula: C₂₁H₂₂O₉

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 418.40

Ref: 3B-L0269

Liquiritin

CAS: 551-15-5

Liquiritin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₁H₂₂O₉

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 418.4

Ref: 11-1368S

(2S)-2-[4-(β-D-Glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one

CAS: 551-15-5

Formula: C₂₁H₂₂O₉

Purity: 96%

Color and Shape: Solid

Molecular weight: 418.3940

Ref: IN-DA00I9U3

Liquiritin

CAS: 551-15-5

Formula: C₂₁H₂₂O₉

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 418.39

Ref: 7W-GC1330

Liquiritin

CAS: 551-15-5

Liquiritin

Purity: 96%

Molecular weight: 418.4g/mol

Ref: 54-OR1025269

Liquiritin

CAS: 551-15-5

Liquiritin

Purity: ≥95%

Molecular weight: 418.39g/mol

Ref: 54-BUP13307

Liquiritin

CAS: 551-15-5

Liquiritin, a flavone compound derived from Glycyrrhiza uralensis, it can effectively reverse alteration in immobility time and sucrose consumption, can increase SOD activity, inhibit lipid peroxidation, and lessen production of MDA, demonstrates that a potential antidepressant-like effect of liquiritin treatment on chronic variable stress can induce depression model rats, which might be related to defense of liquiritin against oxidative stress.

Formula: C₂₁H₂₂O₉

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 418.398

Ref: BP-BP0874

Liquiritin

CAS: 551-15-5

Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.

Formula: C₂₁H₂₂O₉

Purity: 98.16% - 98.66%

Color and Shape: Solid

Molecular weight: 418.39

Ref: TM-T2899

Liquiritin

CAS: 551-15-5

Natural glycoside

Formula: C₂₁H₂₂O₉

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 418.4

Ref: 5G-80490

Liquiritin

Controlled Product

CAS: 551-15-5

Applications Liquiritin is a major constituent of Glycyrrhiza Radix that has a neuroprotective effect against glutamate toxicity in DPC12 cells and may have potential for the treatment of neurodegenerative diseases.
References Teng, L., et. al.: Mol. Med. Reports, 10, 818 (2014)

Formula: C₂₁H₂₂O₉

Color and Shape: Neat

Molecular weight: 418.39

Ref: TR-L468830

Liquiritin

CAS: 551-15-5

Natually produced by plants such as liquorice, liquiritin is formed by the linkage between liquiritigenin and a beta-D-glucopyranosyl residue at position 4. Liquiritin clinical relevance has been as an antiviral and anti-inflammatory agent. In 2020, an artificial intelligent approach has indicated that liquiritin might inhibit SARS-CoV-2 by acting similarly to type I interferon.

Formula: C₂₁H₂₂O₉

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 418.39 g/mol

Ref: 3D-ML08128

LIQUIRITIN

CAS: 551-15-5

Purity: 99%

Molecular weight: 418.3980103

Ref: 10-F859160