CAS 5514-81-8

Betamethasone 21-Acetate-17-propionate

Description:

Betamethasone 21-acetate-17-propionate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is a derivative of betamethasone, which is a potent glucocorticoid used in various medical applications, including the treatment of inflammatory and autoimmune conditions. This compound is characterized by its ability to modulate the immune response and reduce inflammation, making it effective in treating conditions such as allergies, skin disorders, and certain types of arthritis. The chemical structure includes acetate and propionate ester groups, which enhance its pharmacological activity and bioavailability. Betamethasone 21-acetate-17-propionate is typically administered via topical, intramuscular, or intravenous routes, depending on the condition being treated. Its use is associated with potential side effects, including skin thinning, hormonal imbalances, and increased susceptibility to infections, necessitating careful monitoring during treatment. Overall, this compound exemplifies the therapeutic benefits of corticosteroids in managing various inflammatory and autoimmune diseases.

Formula: C₂₇H₃₅FO₇

Synonyms:

• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16β)-
• Betamethasone Dipropionate EP Impurity D
• Betamethasone 21-Acetate-17-propionate
• Betamethasone Dipropionate impurity 3/Betamethasone Dipropionate EP Impurity D/Betamethasone 21-Acetate 17-Propionate
• (11β,16β)-21-(Acetyloxy)-9-fluoro-11-hydroxy-16-Methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
• Betamethasone Dipropionate Impurity 4（Betamethasone Dipropionate EP Impurity D）

Betamethasone Dipropionate EP Impurity D (Betamethasone 21-Acetate 17-Propionate)

CAS: 5514-81-8

Formula: C₂₇H₃₅FO₇

Color and Shape: White To Off-White Solid

Molecular weight: 490.57

Ref: 4Z-B-065002

Betamethasone 21-Acetate 17-Propionate

CAS: 5514-81-8

Impurity Betamethasone Dipropionate EP Impurity D
Applications Betamethasone 21-acetate-17-propionate (Betamethasone Dipropionate EP Impurity D) is a related compound of Betamethasone dipropionate (B327005).
References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),

Formula: C₂₇H₃₅FO₇

Color and Shape: Neat

Molecular weight: 490.561

Ref: TR-B327040

Betamethasone 21-Acetate-d3 17-Propionate

Controlled Product

CAS: 5514-81-8

Applications Labelled Betamethasone 21-acetate-17-propionate (B327040). Betamethasone 21-acetate-17-propionate is a related compound of Betamethasone dipropionate (B327005).
References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),

Formula: C₂₇D₃H₃₂FO₇

Color and Shape: Neat

Molecular weight: 493.579

Ref: TR-B327042

Betamethasone 21-acetate-17-propionate

Controlled Product

CAS: 5514-81-8

Betamethasone 21-acetate-17-propionate is a drug product that is a mixture of betamethasone and betamethasone dipropionate. It is used to treat inflammatory skin conditions such as dermatitis, eczema, psoriasis, and other conditions. Betamethasone 21-acetate-17-propionate is one of the most potent corticosteroids available for topical use. The validation process has been completed on the acetonitrile phase and the reversed phase mobile phase. The validation was successful for both the acetonitrile and reversed phases. A validated HPLC method was developed for this drug product in order to monitor its production process.

Formula: C₂₇H₃₅FO₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 490.56 g/mol

Ref: 3D-FB18566

Betamethasone Dipropionate EP Impurity D

CAS: 5514-81-8

Formula: C₂₇H₃₅FO₇

Molecular weight: 490.57

Ref: ST-EA-CP-B26004