CAS 55142-85-3

Ticlopidine

Description:

Ticlopidine is an antiplatelet medication primarily used to reduce the risk of stroke and other cardiovascular events in patients with a history of atherosclerotic disease. It functions by inhibiting platelet aggregation, thereby preventing blood clots. The chemical formula for ticlopidine is C14H14ClN3S, and it features a thienopyridine structure, which is crucial for its mechanism of action. Ticlopidine is typically administered orally and is metabolized in the liver to its active form, which then interacts with the ADP receptor on platelets. While effective, ticlopidine is associated with potential side effects, including gastrointestinal disturbances and a risk of hematological issues such as thrombocytopenia and neutropenia. Due to these risks, it is often considered a second-line treatment option, with alternatives like clopidogrel being more commonly prescribed. Monitoring of blood counts is recommended during treatment to mitigate adverse effects. Overall, ticlopidine plays a significant role in managing thrombotic disorders, particularly in patients who cannot tolerate other antiplatelet agents.

Formula: C₁₄H₁₄ClNS

InChI: InChI=1S/C14H14ClNS/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14/h1-4,6,8H,5,7,9-10H2

InChI key: InChIKey=PHWBOXQYWZNQIN-UHFFFAOYSA-N

SMILES: C(N1CC2=C(CC1)SC=C2)C3=C(Cl)C=CC=C3

Synonyms:

• 5-[(2-Chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
• Pcr 5332
• Ticlid
• Ticlop
• Ticlopidin
• Ticlopidina
• Ticlopidine
• Tiklyd
• Thieno[3,2-c]pyridine, 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydro-

Ticlopidine

CAS: 55142-85-3

Formula: C₁₄H₁₄ClNS

Purity: 95%

Color and Shape: Solid

Molecular weight: 263.7857

Ref: IN-DA00DDSX

Ticlopidine

CAS: 55142-85-3

Ticlopidine

Purity: ≥98%

Molecular weight: 263.79g/mol

Ref: 54-BUP11415

Ticlopidine

CAS: 55142-85-3

Formula: C₁₄H₁₄ClNS

Molecular weight: 263.79

Ref: 7W-GP4757

5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

CAS: 55142-85-3

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 263.7799987792969

Ref: 10-F320160

Ticlopidine Hydrochloride

CAS: 53885-35-1, 55142-85-3

Formula: C₁₄H₁₄ClNS·HCl

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 300.24

Ref: 3B-T3110

Ticlopidine

CAS: 55142-85-3

Applications Ticlopidine is an antiplatelet drug for the treatment of ischemic heart diseases.
References Rohit, S., et al.: World J. Pharm. Pharm. Sci.,5, 1448 (2016); Hashemzadeh, M., et al.: Cardiovascular Pharmacology: Open Access, 4, 1000128 (2015);

Formula: C₁₄H₁₄ClNS

Color and Shape: Neat

Molecular weight: 263.79

Ref: TR-T889915

Ticlopidine

CAS: 55142-85-3

Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.

Formula: C₁₄H₁₄ClNS

Purity: 99.67%

Color and Shape: Solid

Molecular weight: 263.79

Ref: TM-T4190