CAS 55149-05-8

Pirolate

Description:

Pirolate, with the CAS number 55149-05-8, is a chemical compound that belongs to the class of anticholinergic agents. It is primarily characterized by its ability to inhibit the action of acetylcholine at muscarinic receptors, which can lead to effects such as reduced secretions and smooth muscle relaxation. This compound is often studied for its potential therapeutic applications, particularly in the treatment of conditions like chronic obstructive pulmonary disease (COPD) and asthma, where bronchodilation is desired. Pirolate is typically administered via inhalation to target the respiratory system directly, minimizing systemic side effects. Its pharmacokinetic profile includes a relatively rapid onset of action and a duration that supports its use in managing acute symptoms. Additionally, like other anticholinergics, it may have side effects such as dry mouth, blurred vision, and urinary retention, which are important considerations in clinical use. Overall, pirolate represents a significant option in the pharmacological management of respiratory conditions.

Formula: C₁₆H₁₅N₃O₅

InChI: InChI=1S/C16H15N3O5/c1-4-24-16(21)14-18-13-9(15(20)19-14)5-8-6-11(22-2)12(23-3)7-10(8)17-13/h5-7H,4H2,1-3H3,(H,17,18,19,20)

InChI key: InChIKey=KIDJDJMACBOHKQ-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC=3C(C2)=CC(OC)=C(OC)C3)=NC(C(OCC)=O)=N1

Synonyms:

• Cp 32287
• Cp-32,387
• Ethyl 1,4-dihydro-7,8-dimethoxy-4-oxopyrimido(4,5-b)quinoline-2-carboxylate
• Ethyl 7,8-Dimethoxy-4-Oxo-1,4-Dihydropyrimido[4,5-B]Quinoline-2-Carboxylate
• Ethyl 7,8-dimethoxypyrimido(4,5-b)quinolin-4(3H)-one-2-carboxylate
• Nsc 355079
• Pirolate [USAN:INN]
• Pirolato
• Pirolato [INN-Spanish]
• Pirolatum
• Pirolatum [INN-Latin]
• Pyrimido(4,5-b)quinoline-2-carboxylic acid, 1,4-dihydro-7,8-dimethoxy-4-oxo-, ethyl ester
• Pyrimido[4,5-b]quinoline-2-carboxylic acid, 3,4-dihydro-7,8-dimethoxy-4-oxo-, ethyl ester
• Unii-2Lf7L6Qd58

Ethyl 7,8-dimethoxy-4-oxo-1H-pyrimido[4,5-b]quinoline-2-carboxylate

CAS: 55149-05-8

Ethyl 7,8-dimethoxy-4-oxo-1H-pyrimido[4,5-b]quinoline-2-carboxylate is a prognostic marker for cancer and has been used as an excipient in pharmaceutical dosage forms. It is also used to investigate the cause of fatty acid metabolism disorders in patients with nonalcoholic steatohepatitis (NASH). Ethyl 7,8-dimethoxy-4-oxo-1H-pyrimido[4,5-b]quinoline-2 carboxylate can be reconstituted with water or saline to form a neutral pH solution. The reconstituted solution is stable for up to 2 weeks when stored at 4°C.

Formula: C₁₆H₁₅N₃O₅

Purity: Min. 95%

Molecular weight: 329.31 g/mol

Ref: 3D-FCA14905

Pirolate

CAS: 55149-05-8

Pirolate is a receptor of histamine H1.

Formula: C₁₆H₁₅N₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 329.31

Ref: TM-T16541