CAS 552325-16-3
:A-443654
Description:
A-443654, with the CAS number 552325-16-3, is a small molecule that functions primarily as a selective inhibitor of the protein kinase AKT (also known as protein kinase B). This compound is notable for its role in cancer research, particularly in studies focused on the modulation of cell survival, proliferation, and metabolism, as AKT is a key player in these cellular processes. A-443654 exhibits a high degree of specificity for AKT isoforms, making it a valuable tool for investigating the pathways regulated by this kinase. In terms of its chemical structure, A-443654 contains various functional groups that contribute to its biological activity and solubility properties. The compound has been utilized in preclinical studies to assess its efficacy in inhibiting tumor growth and enhancing the effects of other therapeutic agents. As with many research chemicals, the safety profile and potential side effects are important considerations, and ongoing studies continue to elucidate its pharmacological properties and therapeutic potential.
- (2S)-1-(1H-indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan-2-amine
- 1H-Indole-3-ethanamine, α-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-, (αS)-
- (alphaS)-alpha-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-(S)-1H-indole-3-ethanamine
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Found 3 products.
A-443654
CAS:A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).Formula:C24H23N5OPurity:98.04% - 99.51%Color and Shape:SolidMolecular weight:397.47
