CAS 55268-74-1: Praziquantel

Description: Praziquantel is a synthetic anthelmintic agent primarily used to treat parasitic infections caused by schistosomes and other flatworms. It is characterized by its chemical formula, which includes a unique bicyclic structure that contributes to its efficacy. Praziquantel is typically administered orally and is well-absorbed in the gastrointestinal tract, with peak plasma concentrations occurring within a few hours post-administration. The substance exhibits a broad spectrum of activity against various trematodes and cestodes, leading to increased permeability of the parasite's cell membranes, resulting in paralysis and death of the organism. Praziquantel is generally well-tolerated, with side effects being mild and transient, such as headache or gastrointestinal disturbances. Its pharmacokinetics involve extensive metabolism in the liver, and it is primarily excreted through the urine. The compound is classified under the World Health Organization's List of Essential Medicines, highlighting its importance in global health, particularly in regions where parasitic infections are endemic.

Formula: C₁₉H₂₄N₂O₂

InChI: InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

InChI key: InChIKey=FSVJFNAIGNNGKK-UHFFFAOYSA-N

SMILES: O=C1N2CCC=3C=CC=CC3C2CN(C(=O)C4CCCCC4)C1

Synonyms:

• (±)-Praziquatel
• 2-(Cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one
• 2-(Cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
• 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one
• 2-Cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one
• 2-Cyclohexyl-carbonyl-1,3,4,6,7,11b-hexahydro-2H-pyrazine(2,1-a)isoquinoline-4-one
• 4H-Pyrazino(2,1-A)Isoquinolin-4-One,2-(Cyclohexylcarbonyl)-1,2,3,6,7,11B-Hexah
• 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-
• Azinox
• Benesal
• Biltricide
• Brn 0761557
• Ccris 4114
• Cesol
• Cutter Tape Tabs
• Cysticide
• Distocide
• Droncit
• Drontal
• Drontal Plus
• Embay 8440
• Epiquantel
• Hada Clean
• Prazichantel
• Prazinon
• Praziquantelum
• Praziquentel
• Pyquiton
• Saniquantrel
• Unii-6490C9U457
• Vercom
• Warmnil
• Praziquantel
• 5-24-03-00361 (Beilstein Handbook Reference)

Praziquantel

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 312.41

Praziquantel, 98%

CAS: 55268-74-1

Praziquantel is a potent anthelmintic used against schistosome and many cestode infestations. It is used …

• Formula: C₁₉H₂₄N₂O₂
• Purity: 98%
• Molecular weight: 312.41

Praziquantel for system suitability CRS

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Molecular weight: 312.4061

Praziquantel CRS

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Color and Shape: Crystalline Powder. White. Powder., Crystalline Powder. White. Powder.
• Molecular weight: 312.4061

Praziquantel RS

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Molecular weight: 312.4061

Praziquantel

CAS: 55268-74-1

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

• Formula: C₁₉H₂₄N₂O₂
• Color and Shape: White Powder
• Molecular weight: 312.18378

Praziquantel

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 312.4061

Praziquantel

CAS: 55268-74-1

Praziquantel (Droncit) is an anthelmintic that paralyzes worms by increasing calcium in muscle cells, causing …

• Formula: C₁₉H₂₄N₂O₂
• Purity: 99.69%
• Color and Shape: Solid
• Molecular weight: 312.41

Praziquantel

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Purity: 98.5 - 101.0 % (dried basis)
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 312.41

Praziquantel

CAS: 55268-74-1

• Purity: 98%
• Molecular weight: 312.41g/mol

Praziquantel

CAS: 55268-74-1

• Purity: 99.86%
• Molecular weight: 312.41g/mol

Praziquantel

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 312.42

Praziquantel

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Color and Shape: Neat
• Molecular weight: 312.41

Praziquantel

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Color and Shape: Neat
• Molecular weight: 312.41

Praziquantel 100 µg/mL in Acetonitrile

CAS: 55268-74-1

• Formula: C₁₉H₂₄N₂O₂
• Color and Shape: Single Solution
• Molecular weight: 312.41

2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one

CAS: 55268-74-1

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 312.4129943847656

Praziquantel

CAS: 55268-74-1

Applications Anthelmintic, effective against flatworms. References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 …

• Formula: C₁₉H₂₄N₂O₂
• Color and Shape: White To Off-White
• Molecular weight: 312.41

Praziquantel

CAS: 55268-74-1

Anti-schistosomal; sensory transient receptor potential melastatin type 8 agonist

• Formula: C₁₉H₂₄N₂O₂
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 312.41 g/mol

2-(Descyclohexylcarbonyl)-2-benzoyl-D5 Praziquantel

CAS: 55268-74-1

• Formula: C₁₉D₅H₁₃N₂O₂
• Color and Shape: Neat
• Molecular weight: 311.389