CAS 55268-74-1

Praziquantel

Description:

Praziquantel is a synthetic anthelmintic agent primarily used to treat parasitic infections caused by schistosomes and other flatworms. It is characterized by its chemical formula, which includes a unique bicyclic structure that contributes to its efficacy. Praziquantel is typically administered orally and is well-absorbed in the gastrointestinal tract, with peak plasma concentrations occurring within a few hours post-administration. The substance exhibits a broad spectrum of activity against various trematodes and cestodes, leading to increased permeability of the parasite's cell membranes, resulting in paralysis and death of the organism. Praziquantel is generally well-tolerated, with side effects being mild and transient, such as headache or gastrointestinal disturbances. Its pharmacokinetics involve extensive metabolism in the liver, and it is primarily excreted through the urine. The compound is classified under the World Health Organization's List of Essential Medicines, highlighting its importance in global health, particularly in regions where parasitic infections are endemic.

Formula: C₁₉H₂₄N₂O₂

InChI: InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

InChI key: InChIKey=FSVJFNAIGNNGKK-UHFFFAOYSA-N

SMILES: O=C1N2C(C=3C(CC2)=CC=CC3)CN(C(=O)C4CCCCC4)C1

Synonyms:

• (±)-Praziquatel
• 2-(Cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one
• 2-(Cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
• 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one
• 2-Cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one
• 2-Cyclohexyl-carbonyl-1,3,4,6,7,11b-hexahydro-2H-pyrazine(2,1-a)isoquinoline-4-one
• 4H-Pyrazino(2,1-A)Isoquinolin-4-One,2-(Cyclohexylcarbonyl)-1,2,3,6,7,11B-Hexah
• 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-
• Azinox
• Benesal
• Biltricide
• Brn 0761557
• Ccris 4114
• Cesol
• Cutter Tape Tabs
• Cysticide
• Distocide
• Droncit
• Drontal
• Drontal Plus
• Embay 8440
• Epiquantel
• Hada Clean
• Prazichantel
• Prazinon
• Praziquantelum
• Praziquentel
• Pyquiton
• Saniquantrel
• Unii-6490C9U457
• Vercom
• Warmnil
• Praziquantel

Praziquantel

CAS: 55268-74-1

Formula: C₁₉H₂₄N₂O₂

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 312.41

Ref: 3B-P2125

Praziquantel, 98%

CAS: 55268-74-1

Praziquantel, 98%; Used against schistosome and many cestode infestations. It is used to study voltage-gated Ca2+ channels and is a potential small molecule neurogenic.

Formula: C₁₉H₂₄N₂O₂

Purity: 98%

Molecular weight: 312.41

Ref: 02-J66188

PRAZIQUANTEL FOR SYSTEM SUITABILITY CRS

CAS: 55268-74-1

PRAZIQUANTEL FOR SYSTEM SUITABILITY CRS

Formula: C₁₉H₂₄N₂O₂

Molecular weight: 312.4061

Ref: 41-Y0001533

PRAZIQUANTEL CRS

CAS: 55268-74-1

PRAZIQUANTEL CRS

Formula: C₁₉H₂₄N₂O₂

Color and Shape: Crystalline Powder. White. Powder., Crystalline Powder. White. Powder.

Molecular weight: 312.4061

Ref: 41-P2670000

PRAZIQUANTEL RS

CAS: 55268-74-1

PRAZIQUANTEL RS

Formula: C₁₉H₂₄N₂O₂

Molecular weight: 312.4061

Ref: 41-ICRS0390

Praziquantel

CAS: 55268-74-1

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₁₉H₂₄N₂O₂

Color and Shape: White Powder

Molecular weight: 312.18378

Ref: 45-1554603

Praziquantel

CAS: 55268-74-1

Formula: C₁₉H₂₄N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 312.4061

Ref: IN-DA0035UL

Praziquantel

CAS: 55268-74-1

Praziquantel (Droncit) is an anthelmintic that paralyzes worms by increasing calcium in muscle cells, causing tegument damage and immune response.

Formula: C₁₉H₂₄N₂O₂

Purity: 99.67% - 99.69%

Color and Shape: Solid

Molecular weight: 312.41

Ref: TM-T1435

Praziquantel

CAS: 55268-74-1

Formula: C₁₉H₂₄N₂O₂

Purity: 98.5 - 101.0 % (dried basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 312.41

Ref: 7W-GA8950

Praziquantel

CAS: 55268-74-1

Praziquantel

Purity: 98%

Molecular weight: 312.41g/mol

Ref: 54-OR1029464

Praziquantel

CAS: 55268-74-1

Praziquantel

Purity: ≥98%

Molecular weight: 312.41g/mol

Ref: 54-BUP18078

Praziquantel

CAS: 55268-74-1

Formula: C₁₉H₂₄N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 312.42

Ref: 4Z-P-631

Praziquantel

Controlled Product

CAS: 55268-74-1

Formula: C₁₉H₂₄N₂O₂

Color and Shape: Neat

Molecular weight: 312.41

Ref: 86-MM0615.00

Praziquantel

CAS: 55268-74-1

Formula: C₁₉H₂₄N₂O₂

Color and Shape: White To Off-White

Molecular weight: 312.41

Ref: 04-C16286300

Praziquantel 100 µg/mL in Acetonitrile

CAS: 55268-74-1

Formula: C₁₉H₂₄N₂O₂

Color and Shape: Single Solution

Molecular weight: 312.41

Ref: 04-A16286300AL-100

Praziquantel

CAS: 55268-74-1

Applications Anthelmintic, effective against flatworms.
References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),

Formula: C₁₉H₂₄N₂O₂

Color and Shape: White To Off-White

Molecular weight: 312.41

Ref: TR-P702095

Praziquantel

CAS: 55268-74-1

Anti-schistosomal; sensory transient receptor potential melastatin type 8 agonist

Formula: C₁₉H₂₄N₂O₂

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 312.41 g/mol

Ref: 3D-FP27126

2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one

CAS: 55268-74-1

Formula: C₁₉H₂₄N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 312.413

Ref: 10-F358136

2-(Descyclohexylcarbonyl)-2-benzoyl-D5 Praziquantel

Controlled Product

CAS: 55268-74-1

Formula: C₁₉D₅H₁₃N₂O₂

Color and Shape: Neat

Molecular weight: 311.389

Ref: TR-D281967