CAS 55268-75-2

Cefuroxime

Description:

Cefuroxime is a broad-spectrum cephalosporin antibiotic that is effective against a variety of bacterial infections. It is classified as a second-generation cephalosporin and is commonly used to treat respiratory tract infections, urinary tract infections, and skin infections, among others. Cefuroxime operates by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The substance is typically administered in its axetil form, which enhances its oral bioavailability. Cefuroxime is known for its stability against certain beta-lactamases, making it effective against some resistant strains of bacteria. It is generally well-tolerated, though potential side effects can include gastrointestinal disturbances, allergic reactions, and, in rare cases, hematological effects. The chemical structure of cefuroxime includes a beta-lactam ring, which is essential for its antibacterial activity. As with all antibiotics, it is crucial to use cefuroxime judiciously to minimize the development of antibiotic resistance.

Formula: C₁₆H₁₆N₄O₈S

InChI: InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1

InChI key: InChIKey=JFPVXVDWJQMJEE-IZRZKJBUSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CC=CO3)=O)C2=O)(SCC1COC(N)=O)[H]

Synonyms:

• (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[furan-2-yl(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1-(acetyloxy)ethyl (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, [6R-[6α,7β(Z)]]-
• Biofuroksym
• Biofuroxim
• Cefaloxime
• Cefasyn
• Cefuroxime
• Cefuroxime Acid
• Cefuroxime,Free Acid
• Cefuroximo
• Cephuroxime
• Ketocef
• Maxalac

Cefuroxime

CAS: 55268-75-2

Formula: C₁₆H₁₆N₄O₈S

Purity: ≥ 97.0%

Color and Shape: White to off-white or pale yellow powder or granules

Molecular weight: 424.39

Ref: 7W-GA9610

Cefuroxime

CAS: 55268-75-2

Cefuroxime

Formula: C₁₆H₁₆N₄O₈S

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 424.39

Ref: 54-BUP11065

Cefuroxime

CAS: 55268-75-2

Cefuroxime

Formula: C₁₆H₁₆N₄O₈S

Purity: ≥98%

Molecular weight: 424.39

Ref: 54-OR1025398

Cefuroxime

Controlled Product

CAS: 55268-75-2

Formula: C₁₆H₁₆N₄O₈S

Color and Shape: Neat

Molecular weight: 424.39

Ref: 86-MM1341.10

Cefuroxime 1000 µg/mL in Acetonitrile

Controlled Product

CAS: 55268-75-2

Formula: C₁₆H₁₆N₄O₈S

Color and Shape: Single Solution

Molecular weight: 424.39

Ref: 04-A11065290AL-1000

Cefuroxime

CAS: 55268-75-2

Formula: C₁₆H₁₆N₄O₈S

Purity: 98%

Color and Shape: Solid

Molecular weight: 424.3852

Ref: IN-DA00I9UU

Cefuroxime-d3

Controlled Product

CAS: 55268-75-2

Applications Labelled Cefuroxime (C248050). Antibacterial.
References O’Callaghan, C.H., et al.: Antimicrob. Agents Chemother., 9, 511 (1976), Norrby, R., et al.: J. Antimicrob. Chemother., 3, 355 (1977), Brogden, R.N., et al.: Drugs, 17, 233 (1979), Wozniak, J.R., et al.: Anal. Profiles Drug Subs., 20, 209 (1991),

Formula: C₁₆H₁₃D₃N₄O₈S

Color and Shape: Neat

Molecular weight: 427.4

Ref: TR-C248052

Cefuroxime

CAS: 55268-75-2

Applications Cefuroxime is a second-generation cephalosporin antibiotic.

Formula: C₁₆H₁₆N₄O₈S

Color and Shape: Neat

Molecular weight: 424.39

Ref: TR-C248088

Cefuroxime

CAS: 55268-75-2

Formula: C₁₆H₁₆N₄O₈S

Molecular weight: 424.38

Ref: ST-EA-CP-C265000

Cefuroxime Axetil EP Impurity D

CAS: 55268-75-2

Formula: C₁₆H₁₆N₄O₈S

Molecular weight: 424.39

Ref: ST-EA-CP-C92018

Cefuroxime

CAS: 55268-75-2

Cefuroxime (Cephuroxime) is a second-generation cephalosporin antibiotic with antimicrobial activity for the study of soft tissue infections.

Formula: C₁₆H₁₆N₄O₈S

Purity: 98.32%

Color and Shape: Solid

Molecular weight: 424.39

Ref: TM-T65068

Cefuroxime

CAS: 55268-75-2

Cefuroxime is a second-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating respiratory tract infections, urinary tract infections, and Lyme disease.

Formula: C₁₆H₁₆N₄O₈S

Purity: Min. 98.0 Area-%

Color and Shape: White Orange Powder

Molecular weight: 424.39 g/mol

Ref: 3D-FA19881