CAS 55285-45-5

Pirifibrate

Description:

Pirifibrate is a synthetic compound classified as a fibrate, primarily used in the management of dyslipidemia, particularly to lower triglyceride levels and increase high-density lipoprotein (HDL) cholesterol. Its chemical structure features a phenoxy group, which contributes to its pharmacological activity. Pirifibrate acts as a peroxisome proliferator-activated receptor (PPAR) agonist, influencing lipid metabolism and promoting the breakdown of fatty acids. The substance is typically administered orally and is known for its relatively favorable safety profile, although potential side effects may include gastrointestinal disturbances and muscle-related issues. Pirifibrate is often utilized in combination with other lipid-lowering agents to enhance therapeutic efficacy. Its solubility characteristics and stability under various conditions are important for formulation and delivery in pharmaceutical applications. As with any medication, it is essential to consider contraindications and interactions with other drugs when prescribing pirifibrate. Overall, its role in lipid management underscores the importance of fibrates in cardiovascular health.

Formula: C₁₇H₁₈ClNO₄

InChI: InChI=1S/C17H18ClNO4/c1-17(2,23-15-8-6-12(18)7-9-15)16(21)22-11-14-5-3-4-13(10-20)19-14/h3-9,20H,10-11H2,1-2H3

InChI key: InChIKey=YJBIJSVYPHRVCI-UHFFFAOYSA-N

SMILES: O(C(C(OCC=1N=C(CO)C=CC1)=O)(C)C)C2=CC=C(Cl)C=C2

Synonyms:

• EL 466
• Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, [6-(hydroxymethyl)-2-pyridinyl]methyl ester
• Pirifibrate
• Bratenol

Pirifibrate

CAS: 55285-45-5

Pirifibrate (EL-466) can be used in the hyperlipoproteinemias research that is a hypolipemic substance [1].

Formula: C₁₇H₁₈ClNO₄

Color and Shape: Solid

Molecular weight: 335.78

Ref: TM-T61041