CAS 55297-95-5

Tiamulin

Description:

Tiamulin is a synthetic antibiotic belonging to the pleuromutilin class, primarily used in veterinary medicine for the treatment of bacterial infections in livestock, particularly in pigs and poultry. It exhibits broad-spectrum activity against various Gram-positive bacteria and some Gram-negative bacteria, making it effective against respiratory and enteric infections. Tiamulin works by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit. The substance is typically administered orally or via injection, and its pharmacokinetics indicate good absorption and distribution in animal tissues. Tiamulin is known for its low toxicity in animals, but care must be taken regarding its use in food-producing animals due to potential residues in meat products. Regulatory agencies have established guidelines for its use to ensure food safety. Additionally, resistance to tiamulin can develop, necessitating prudent use in veterinary practices to maintain its efficacy. Overall, tiamulin is a valuable tool in veterinary medicine, contributing to the health and productivity of livestock.

Formula: C₂₈H₄₇NO₄S

InChI: InChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1

InChI key: InChIKey=UURAUHCOJAIIRQ-QGLSALSOSA-N

SMILES: C[C@@H]1[C@]23[C@]([C@](C)([C@H](OC(CSCCN(CC)CC)=O)C[C@](C=C)(C)[C@H]1O)[C@H](C)CC2)(C(=O)CC3)[H]

Synonyms:

• (1S,2R,3S,4S,6R,7S,14R)-6-((2-Diethylaminoethylthio)Acetoxy)-3-Hydroxy-2,4,7,14-Tetramethyl-4-Vinyltricyclo(5,4,3,01.8)Tetradecan-9-One
• (3aS,4R,5S,6S,8R,9R,9aR)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate
• (4R,5S,6S,8R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate
• 3a,9-Propano-3aH-cyclopentacyclooctene, acetic acid deriv.
• Acetic acid, 2-[[2-(diethylamino)ethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
• Acetic acid, [[2-(diethylamino)ethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
• Acetic acid, [[2-(diethylamino)ethyl]thio]-, 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, [3aS-(3aα,4β,5α,6α,8β,9α,9aβ,10S*)]-
• Denagard
• Thiamutilin
• Tiavet P
• Tiamulin

Tiamulin

CAS: 55297-95-5

Antibiotics nesoi

Formula: C₂₈H₄₇NO₄S

Color and Shape: Translucent Yellow Solid

Molecular weight: 493.75 g/mol

Ref: 45-1667355

Tiamulin

CAS: 55297-95-5

Tiamulin

Formula: C₂₈H₄₇NO₄S

Purity: ≥98%

Molecular weight: 493.74

Ref: 54-BUP17282

Acetic acid, [[2-(diethylamino)ethyl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-ylester

CAS: 55297-95-5

Formula: C₂₈H₄₇NO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 493.7421

Ref: IN-DA00I9V4

Tiamulin

CAS: 55297-95-5

Tiamulin

Formula: C₂₈H₄₇NO₄S

Color and Shape: Solid

Molecular weight: 493.74207

Ref: 54-BIT0156

Tiamulin

Controlled Product

CAS: 55297-95-5

Formula: C₂₈H₄₇NO₄S

Color and Shape: Neat

Molecular weight: 493.74

Ref: 04-C17575790

Tiamulin (Standard)

CAS: 55297-95-5

Tiamulin (Standard) is the standard substance of Tiamulin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tiamulin (Thiamutilin) is a semisynthetic pleuromutilin antibiotic

Formula: C₂₈H₄₇NO₄S

Color and Shape: Solid

Molecular weight: 493.74

Ref: TM-TMSM-2249

Tiamulin-13C4 Fumarate

CAS: 55297-95-5

Stability Hygroscopic
Applications Labelled Tiamulin (T436600). A derivative of Pleuromutilin. Antibacterial.
References Egger, H., et al.: J. Antibiot., 29, 923 (1976), Baughn, C.O., et al.: Avian Dis., 22, 620 (1978), Goodwin, R.F., et al.: Vet. Rec., 104, 194 (1979), Kitai, K., et al.: Antimicrob. Agents Chemother., 31, 1935 (1987), Aarestrup, F., et al.: Vet. Microbiol., 64, 299 (1999),

Formula: C₂₈₁₃C₄H₅₁NO₈S

Color and Shape: Neat

Molecular weight: 613.78

Ref: TR-T436603

Tiamulin

CAS: 55297-95-5

Applications Tiamulin is a derivative of Pleuromutilin. Antibacterial.
References Egger, H., et al.: J. Antibiot., 29, 923 (1976), Baughn, C.O., et al.: Avian Dis., 22, 620 (1978), Goodwin, R.F., et al.: Vet. Rec., 104, 194 (1979), Kitai, K., et al.: Antimicrob. Agents Chemother., 31, 1935 (1987), Aarestrup, F., et al.: Vet. Microbiol., 64, 299 (1999),

Formula: C₂₈H₄₇NO₄S

Color and Shape: Neat

Molecular weight: 493.74

Ref: TR-T436595

Tiamulin

CAS: 55297-95-5

Tiamulin (Thiamutilin) is a semisynthetic pleuromutilin antibiotic

Formula: C₂₈H₄₇NO₄S

Purity: 99.60% - 99.85%

Color and Shape: Transparent Oil

Molecular weight: 493.742

Ref: TM-T8065

Tiamulin

CAS: 55297-95-5

Tiamulin is a sodium salt of tiamulin, which is an antibacterial agent. Tiamulin can be used in vitro to test the efficacy of antibiotics against bacteria. It has been shown that tiamulin inhibits protein synthesis and bacterial growth by binding to the ribosomal RNA molecule. Tiamulin also has a low toxicity profile in vivo and can be used to treat infectious diseases. Acute toxicities have been observed at higher doses, but are not significant when administered at the recommended therapeutic dose.

Formula: C₂₈H₄₇NO₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 493.74 g/mol

Ref: 3D-FT31902

Tiamulin fumarate in Methanol

CAS: 55297-95-5

Methanol

Formula: C₂₈H₄₇NO₄S

Molecular weight: 493.7

Ref: BE-BePure-26051YM-1000

Tiamulin

CAS: 55297-95-5

Formula: C₂₈H₄₇NO₄S

Molecular weight: 493.7

Ref: BE-BePure-26051

Tiamulin

CAS: 55297-95-5

Formula: C₂₈H₄₇NO₄S

Molecular weight: 493.75

Ref: ST-EA-CP-T154000