CAS 55300-29-3

Antrafenine

Description:

Antrafenine, with the CAS number 55300-29-3, is a chemical compound that belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is primarily recognized for its analgesic and anti-inflammatory properties, making it useful in the treatment of pain and inflammation. Antrafenine is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins, compounds that mediate inflammation and pain. The substance is typically administered in various formulations, and its pharmacokinetics may involve absorption, distribution, metabolism, and excretion processes that vary among individuals. Safety and efficacy profiles are essential considerations in its use, as with any medication, and potential side effects may include gastrointestinal disturbances or allergic reactions. As with all pharmaceuticals, it is important to use Antrafenine under medical supervision to ensure appropriate dosing and to monitor for any adverse effects.

Formula: C₃₀H₂₆F₆N₄O₂

InChI: InChI=1S/C30H26F6N4O2/c31-29(32,33)20-4-3-5-22(18-20)40-14-12-39(13-15-40)16-17-42-28(41)24-6-1-2-7-25(24)38-26-10-11-37-27-19-21(30(34,35)36)8-9-23(26)27/h1-11,18-19H,12-17H2,(H,37,38)

InChI key: InChIKey=NWGGKKGAFZIVBJ-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C=C(C(F)(F)F)C=C2)N=CC1)C3=C(C(OCCN4CCN(CC4)C5=CC(C(F)(F)F)=CC=C5)=O)C=CC=C3

Synonyms:

• 2-(4-(alpha,alpha,alpha-Trifluoro-m-tolyl)-1-piperazinyl)ethyl N-(7-(trifluoromethyl)-4-quinolyl)anthranilate
• 2-(7-Trifluormethyl-4-chinolylamino)benzoesaeure-2-(4-(3-trifluormethylphenyl)-1-piperazinyl)ethylester
• 2-{4-[3-(Trifluoromethyl)Phenyl]Piperazin-1-Yl}Ethyl 2-{[7-(Trifluoromethyl)Quinolin-4-Yl]Amino}Benzoate
• 4-(3-Trifluoromethyl)phenylpiperazineethanol o-(7-trifluoromethyl-4-quinolylamino)benzoate
• Antrafenine [INN]
• Antrafenino
• Antrafenino [INN-Spanish]
• Antrafeninum
• Antrafeninum [INN-Latin]
• Benzoic acid, 2-((7-(trifluoromethyl)-4-quinolinyl)amino)-, 2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl ester
• Brn 0600911
• Piperazineethanol, 4-(alpha,alpha,alpha-trifluoro-m-tolyl)-, N-(7-trifluoromethyl-4-quinolyl)anthranilate
• Sl 73-033
• Stakan
• Stakane
• Unii-21Fs93Y6Oe

Antrafenine Hydrochloride

Controlled Product

CAS: 55300-29-3, 55300-30-6

Stability Hygroscopic
Applications A new analgesic.
References de Julian-Ortiz, J., et al.: J. Med. Chem., 42, 3308 (1999), Roy, K., et al.: Bioorg. Med. Chem., 12, 745 (2004), Garcia-Garcia, A., et al.: J. Antimicrob. Chemother., 53, 65 (2004),

Formula: C₃₀H₂₆F₆N₄O₂xHCl

Color and Shape: Neat

Molecular weight: 588.54

Ref: TR-A697800