CAS 55300-30-6

Benzoic acid, 2-[[7-(trifluoromethyl)-4-quinolinyl]amino]-, 2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl ester, hydrochloride (1:2)

Description:

Benzoic acid, 2-[[7-(trifluoromethyl)-4-quinolinyl]amino]-, 2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl ester, hydrochloride (1:2) is a complex organic compound characterized by its structural components, which include a benzoic acid moiety, a quinoline derivative, and a piperazine group. The presence of trifluoromethyl groups enhances its lipophilicity and may influence its biological activity. This compound is typically a white to off-white solid and is soluble in polar organic solvents. Its hydrochloride form indicates that it is a salt, which can improve its stability and solubility in aqueous environments. The compound may exhibit pharmacological properties, potentially acting as a pharmaceutical agent due to the presence of the quinoline and piperazine structures, which are often associated with various biological activities. Safety and handling precautions should be observed, as with many chemical substances, particularly those with halogenated groups, which can pose environmental and health risks.

Formula: C₃₀H₂₆F₆N₄O₂·2ClH

InChI: InChI=1S/C30H26F6N4O2.2ClH/c31-29(32,33)20-4-3-5-22(18-20)40-14-12-39(13-15-40)16-17-42-28(41)24-6-1-2-7-25(24)38-26-10-11-37-27-19-21(30(34,35)36)8-9-23(26)27;;/h1-11,18-19H,12-17H2,(H,37,38);2*1H

InChI key: InChIKey=GEZLWXYIFNEJBC-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C=C(C(F)(F)F)C=C2)N=CC1)C3=C(C(OCCN4CCN(CC4)C5=CC(C(F)(F)F)=CC=C5)=O)C=CC=C3.Cl

Synonyms:

• Benzoic acid, 2-[[7-(trifluoromethyl)-4-quinolinyl]amino]-, 2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl ester, dihydrochloride
• Benzoic acid, 2-[[7-(trifluoromethyl)-4-quinolinyl]amino]-, 2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl ester, hydrochloride (1:2)

Antrafenine Hydrochloride

Controlled Product

CAS: 55300-29-3, 55300-30-6

Stability Hygroscopic
Applications A new analgesic.
References de Julian-Ortiz, J., et al.: J. Med. Chem., 42, 3308 (1999), Roy, K., et al.: Bioorg. Med. Chem., 12, 745 (2004), Garcia-Garcia, A., et al.: J. Antimicrob. Chemother., 53, 65 (2004),

Formula: C₃₀H₂₆F₆N₄O₂xHCl

Color and Shape: Neat

Molecular weight: 588.54

Ref: TR-A697800

Antrafenine hydrochloride

CAS: 55300-30-6

Antrafenine hydrochloride is a drug repositioning agent. It is a prodrug that is converted to its active form, antrafenine, by the enzyme dehydrogenase in vivo. Antrafenine hydrochloride has been shown to be effective in treating chronic kidney disease (CKD) in animal models and cell culture studies. It has also been shown to be an effective analgesic for cancer pain and inflammatory diseases. Antrafenine hydrochloride has been used as a growth factor for wound healing and tissue regeneration, as well as being biocompatible with various polymers including polylactic acid (PLA), polyglycolic acid (PGA) and hyaluronic acid (HA).

Formula: C₃₀H₂₆F₆N₄O₂·xHCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 588.54 g/mol

Ref: 3D-FA17950