CAS 55314-16-4

3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one

Description:

3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, with the CAS number 55314-16-4, is an organic compound characterized by its unique structure that includes a dimethylamino group and a pyridine ring. This compound typically exhibits properties associated with both amines and carbonyl compounds, making it a versatile intermediate in organic synthesis. It is often used in the development of pharmaceuticals and agrochemicals due to its potential biological activity. The presence of the pyridine moiety can contribute to its solubility in polar solvents, while the propenone structure may allow for reactivity in various chemical transformations, such as Michael additions or condensation reactions. Additionally, this compound may display distinct optical properties, which can be leveraged in applications involving dyes or sensors. Safety data should be consulted for handling, as compounds with amine functionalities can sometimes be hazardous. Overall, 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one is a significant compound in synthetic organic chemistry with various potential applications.

Formula: C₁₀H₁₂N₂O

InChI: InChI=1/C10H12N2O/c1-12(2)8-5-10(13)9-3-6-11-7-4-9/h3-8H,1-2H3/b8-5+

InChI key: InChIKey=MZLRFUCMBQWLNV-UHFFFAOYSA-N

SMILES: C(C=CN(C)C)(=O)C=1C=CC=NC1

Synonyms:

• (2E)-3-(dimethylamino)-1-pyridin-3-ylprop-2-en-1-one
• (2E)-3-(dimethylamino)-1-pyridin-4-ylprop-2-en-1-one
• 2-Propen-1-one, 3-(dimethylamino)-1-(3-pyridinyl)-
• 3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one
• 3-(Dimethylamino)-1-(Pyridin-3-Yl)Prop-2-En-1-One
• 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one
• 3-Dimethylamino-1-(pyridin-3-yl)propenone
• 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
• 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ,97%
• 1-(3-PYRIDYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE 95%
• 3-(Dimethylamino)-1-pyridin-3-ylprop-2-en-1-one

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

CAS: 55314-16-4

Formula: C₁₀H₁₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 176.2151

Ref: IN-DA003CXR

3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

CAS: 55314-16-4

3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

Formula: C₁₀H₁₂N₂O

Purity: 96%

Color and Shape: brown solid

Molecular weight: 176.22g/mol

Ref: 54-OR14051

Imatinib EP Impurity A

CAS: 55314-16-4

Formula: C₁₀H₁₂N₂O

Molecular weight: 176.22

Ref: ST-EA-CP-I5001

3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one

Controlled Product

CAS: 55314-16-4

Impurity EP Impurity A
Applications 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one (Imatinib EP Impurity A) is an Imatinib intermediate. It is a COVID19-related research product.
References Bennett, G., et al.: J. Med. Chem., 21, 623 (1978), Buchdunger, E., et al.: J. Pharmacol. Exp. Ther., 295, 139 (2000), Krystal, G., et al.: Clin. Cancer Res., 6, 3319 (2000), van Oosterom, A., et al.: Lancet, 358, 1421 (2001),

Formula: C₁₀H₁₂N₂O

Color and Shape: Neat

Molecular weight: 176.22

Ref: TR-D462145

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

CAS: 55314-16-4

Formula: C₁₀H₁₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 176.219

Ref: 10-F047914

3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one

CAS: 55314-16-4

3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one is a synthetic anticancer compound. It is an amide derivative of 3-dimethylamino-1-(3-pyridyl)-2-propenal, which is synthesized by reacting 3,5,6,7 tetrahydrobenzo[b]thiophene with 3-(dimethylamino)acrylic acid chloride. The synthesis of 3DAP was reported in 1974 by Novartis Pharmaceuticals Corporation and it has been used as a lead compound for the development of other anticancer agents. This drug can inhibit the growth of myelogenous leukemia cells and has been shown to be effective against cancer cells that are resistant to imatinib.

Formula: C₁₀H₁₂N₂O

Purity: Min. 95%

Color and Shape: Off-White To Yellow Solid

Molecular weight: 176.22 g/mol

Ref: 3D-FD22332