CAS 5536-17-4: Vidarabine
Description:Vidarabine, also known as adenine arabinoside, is an antiviral nucleoside analog primarily used in the treatment of viral infections, particularly herpes simplex virus and varicella-zoster virus. It is characterized by its structure, which includes an arabinose sugar moiety linked to an adenine base, distinguishing it from natural nucleosides. Vidarabine exhibits its antiviral activity by inhibiting viral DNA synthesis, thereby preventing the replication of the virus. The compound is typically administered intravenously due to its poor oral bioavailability. It has a relatively short half-life, necessitating careful dosing and monitoring during treatment. Vidarabine can cause side effects, including neurotoxicity and hematological issues, which require consideration in clinical settings. Its use has declined with the advent of more effective antiviral agents, but it remains a significant compound in the study of antiviral therapies. As a chemical entity, Vidarabine is classified under the category of purine nucleosides and has a specific CAS number, 5536-17-4, which is used for its identification in chemical databases.
Formula:C10H13N5O4
InChI:InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1
InChI key:InChIKey=OIRDTQYFTABQOQ-UHTZMRCNSA-N
SMILES:OCC1OC(N2C=NC=3C(=NC=NC32)N)C(O)C1O
- Synonyms:
- 6-Amino-9-beta-D-arabinofuranosylpurine
- 6-Amino-9-β-<span class="text-smallcaps">D</span>-arabinofuranosylpurine
- 6-Amino-9-β-D-arabinofuranosylpurine
- 9-(beta-D-Arabinofuranosyl)-9H-purin-6-amine
- 9-(beta-D-glycero-Pentofuranosyl)-9H-purin-6-amine
- 9-Arabinosyladenine
- 9-beta-D-Arabinofuranosyladenine
- 9-β-<span class="text-smallcaps">D</span>-Arabinoadenosine
- 9-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-9H-purin-6-amine
- 9-β-<span class="text-smallcaps">D</span>-Arabinofuranosyladenine
- See more synonyms
- 9-β-<span class="text-smallcaps">D</span>-Arabinosyladenine
- 9-β-D-Arabinoadenosine
- 9-β-D-Arabinofuranosyl-9H-purin-6-amine
- 9-β-D-Arabinofuranosyl-adenine
- 9-β-D-Arabinofuranosyladenine
- 9-β-D-Arabinosyladenine
- 9-β-D-arabinopyranosyl-9H-purin-6-amine
- 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-
- 9H-Purin-6-amine, 9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
- 9H-Purin-6-amine, 9-β-D-arabinofuranosyl-
- 9H-purin-6-amine, 9-beta-D-glycero-pentofuranosyl-
- Adenine 9-β-<span class="text-smallcaps">D</span>-arabinofuranoside
- Adenine 9-β-D-arabinofuranoside
- Adenine arabinoside
- Adenine β-<span class="text-smallcaps">D</span>-arabinofuranoside
- Adenine β-D-arabinofuranoside
- Adenine, 9-beta-D-arabinofuranosyl-
- Adenine, 9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
- Adenine, 9-β-D-arabinofuranosyl-
- Ara-A
- Araadenosine
- Arabinosyladenine
- Arasena-A
- Ci-673
- Nqz-071
- Nsc 247519
- Nsc 404241
- Spongoadenosine
- Vidarabin
- Vidarabina
- Vidarabine anhydrous
- Vira-A
- β-<span class="text-smallcaps">D</span>-Arabinofuranosyladenine
- β-<span class="text-smallcaps">D</span>-Arabinosyladenine
- β-Ara-A
- β-D-Arabinofuranosyladenine
- β-D-Arabinosyladenine
